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6/14/2020 1:45:26 PM | Browse: 85 | Download: 57
Publication Name World Journal of Gastroenterology
Manuscript ID 53800
Country/Territory Russia
Received
2019-12-30 12:41
Peer-Review Started
2019-12-30 12:44
To Make the First Decision
Return for Revision
2020-01-19 18:41
Revised
2020-05-13 15:05
Second Decision
2020-05-25 10:18
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2020-05-26 02:38
Articles in Press
2020-05-26 02:38
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2020-06-12 08:46
Publish the Manuscript Online
2020-06-14 13:45
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology and Hepatology
Manuscript Type Review
Article Title Regenerative medicine of pancreatic islets
Manuscript Source Invited Manuscript
All Author List Irina V Arutyunyan, Timur Kh Fatkhudinov, Andrey V Makarov, Andrey V Elchaninov and Gennady T Sukhikh
ORCID
Author(s) ORCID Number
Irina V Arutyunyan http://orcid.org/0000-0002-4344-8943
Timur Kh Fatkhudinov http://orcid.org/0000-0002-6498-5764
Andrey V Makarov http://orcid.org/0000-0003-2133-2293
Andrey V Elchaninov http://orcid.org/0000-0002-2392-4439
Gennady T Sukhikh http://orcid.org/0000-0003-0214-1213
Funding Agency and Grant Number
Funding Agency Grant Number
President Grant for Government Support of Young Russian Scientists 075-15-2019-1120
Corresponding author Timur Kh Fatkhudinov, DSc, MD, PhD, Academic Research, Laboratory of Growth and Development, Scientific Research Institute of Human Morphology, 3 Tsurupa Street, Moscow 117418, Russia, Moscow 117418, Russia. tfat@yandex.ru
Key Words Pancreas; Islets of Langerhans; β-cells; Regeneration; Replacement; Transplantation
Core Tip The review discusses the most promising strategies for regenerative medicine to stimulate the regeneration or replacement of the islet of the pancreas. The “regeneration” strategy aims to maintain a preserved population of β-cells through replication, or evoke the intrinsic adaptive mechanisms. The “replacement” strategy implies transplantation of β-cells or β-like cells obtained ex vivo from progenitors or mature somatic cells (hepatocytes or α-cells). We believe that the huge volume of experimental and clinical studies currently under way will finally allow a safe and effective solution to simple goal-restoration of the active β-cells.
Publish Date 2020-06-14 13:45
Citation Arutyunyan IV, Fatkhudinov TK, Makarov AV, Elchaninov AV, Sukhikh GT. Regenerative medicine of pancreatic islets. World J Gastroenterol 2020; 26(22): 2948-2966
Url https://www.wjgnet.com/1007-9327/full/v26/i22/2948.htm
DOI https://dx.doi.org/10.3748/wjg.v26.i22.2948
Full Article (PDF) WJG-26-2948.pdf
Full Article (Word) WJG-26-2948.docx
Manuscript File 53800-Review.docx
Answering Reviewers 53800-Answering reviewers.pdf
Audio Core Tip 53800-Audio core tip.m4a
Conflict-of-Interest Disclosure Form 53800-Conflict-of-interest statement.pdf
Copyright License Agreement 53800-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 53800-Grant application form(s).pdf
Non-Native Speakers of English Editing Certificate 53800-Language certificate.pdf
Peer-review Report 53800-Peer-review(s).pdf
Scientific Misconduct Check 53800-Scientific misconduct check.pdf
Scientific Editor Work List 53800-Scientific editor work list.pdf