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8/25/2020 9:16:00 AM | Browse: 464 | Download: 834
Publication Name World Journal of Hepatology
Manuscript ID 55702
Country United States
2020-03-31 15:53
Peer-Review Started
2020-03-31 15:58
To Make the First Decision
Return for Revision
2020-07-05 14:53
2020-07-08 03:00
Second Decision
2020-07-21 09:23
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2020-07-26 21:28
Articles in Press
2020-07-26 21:28
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2020-08-05 11:27
Publish the Manuscript Online
2020-08-25 09:16
ISSN 1948-5182 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Case Report
Article Title Non-islet cell tumor hypoglycemia as an initial presentation of hepatocellular carcinoma coupled with end-stage liver cirrhosis: A case report and literature review
Manuscript Source Unsolicited Manuscript
All Author List Bo Yu, Rana Douli, Jose Amaya Suarez, Victor Perez Gutierrez, Mohammad Aldiabat and Maria Khan
Author(s) ORCID Number
Bo Yu http://orcid.org/0000-0002-7520-453X
Rana Douli http://orcid.org/0000-0002-3200-214X
Jose Amaya Suarez http://orcid.org/0000-0001-3330-412X
Victor Perez Gutierrez http://orcid.org/0000-0002-5028-623X
Mohammad Aldiabat http://orcid.org/0000-0002-7023-964X
Maria Khan http://orcid.org/0000-0002-5100-747X
Funding Agency and Grant Number
Corresponding Author Bo Yu, MD, MSc, Doctor, Department of Medicine, Lincoln Medical Center, 234 E.149th Street, Bronx, NY 10451-5504, United States. yub3@nychhc.org
Key Words Non-islet cell tumor hypoglycemia; Hepatocellular carcinoma; Liver cirrhosis; Insulin-like growth factor-2; Paraneoplastic syndrome; Case report
Core Tip Paraneoplastic Non-islet cell tumor hypoglycemia can occur as an initial presentation in patients with hepatocellular carcinoma and is often difficult to correct. It is tend to be underdiagnosed because patients often developed tolerance to chronic fasting hypoglycemia secondary to advanced liver cirrhosis. A ratio of insulin-like growth factor-2/insulin-like growth factor-1 above 10 is often found if non-islet cell tumor hypoglycemia is induced by overproduction of incompletely processed insulin-like growth factor-2. Oral corticosteroids and frequent high carbohydrate meals are often recommended but the outcome is unfavorable in general if tumor removal is not possible.
Publish Date 2020-08-25 09:16
Citation Yu B, Douli R, Suarez JA, Gutierrez VP, Aldiabat M, Khan M. Non-islet cell tumor hypoglycemia as an initial presentation of hepatocellular carcinoma coupled with end-stage liver cirrhosis: A case report and review of literature. World J Hepatol 2020; 12(8): 519-524
URL https://www.wjgnet.com/1948-5182/full/v12/i8/519.htm
DOI https://dx.doi.org/10.4254/wjh.v12.i8.519
Full Article (PDF) WJH-12-519.pdf
Full Article (Word) WJH-12-519.docx
CARE Checklist–2016 55702-CARE-Checklist–2016-revision.pdf
Manuscript File 55702-Review.docx
Answering Reviewers 55702-Answering reviewers.pdf
Audio Core Tip 55702-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 55702-Conflict-of-interest statement.pdf
Copyright License Agreement 55702-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s) 55702-Informed consent statement.pdf
Peer-review Report 55702-Peer-review(s).pdf
Scientific Misconduct Check 55702-Scientific misconduct check.pdf
Scientific Editor Work List 55702-Scientific editor work list.pdf