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8/14/2020 12:33:31 PM | Browse: 642 | Download: 1693
Publication Name World Journal of Gastroenterology
Manuscript ID 56043
Country/Territory China
Received
2020-04-22 07:13
Peer-Review Started
2020-04-22 07:14
To Make the First Decision
Return for Revision
2020-06-13 02:54
Revised
2020-06-24 23:31
Second Decision
2020-07-15 13:07
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2020-07-16 01:51
Articles in Press
2020-07-16 01:51
Publication Fee Transferred
Edit the Manuscript by Language Editor
2020-07-28 02:17
Typeset the Manuscript
2020-08-14 00:49
Publish the Manuscript Online
2020-08-14 12:33
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Retrospective Study
Article Title High levels of serum interleukin-6 increase mortality of hepatitis B virus-associated acute-on-chronic liver failure
Manuscript Source Unsolicited Manuscript
All Author List Chao Zhou, Ning Zhang, Ting-Ting He, Yao Wang, Li-Fu Wang, Yong-Qiang Sun, Jing Jing, Jing-Jing Zhang, Shuang-Nan Fu, Xuan Wang, Xiao-Xiao Liang, Xin Li, Man Gong and Jun Li
ORCID
Author(s) ORCID Number
Chao Zhou http://orcid.org/0000-0002-2665-2889
Ning Zhang http://orcid.org/0000-0002-6826-9175
Ting-Ting He http://orcid.org/0000-0003-1947-5308
Yao Wang http://orcid.org/0000-0002-4651-3077
Li-Fu Wang http://orcid.org/0000-0002-1419-4809
Yong-Qiang Sun http://orcid.org/0000-0001-6340-158X
Jing Jing http://orcid.org/0000-0002-6290-6268
Jing-Jing Zhang http://orcid.org/0000-0002-0207-9053
Shuang-Nan Fu http://orcid.org/0000-0001-8278-4555
Xuan Wang http://orcid.org/0000-0003-2526-008X
Xiao-Xiao Liang http://orcid.org/0000-0002-4067-6473
Xin Li http://orcid.org/0000-0002-4930-5433
Man Gong http://orcid.org/0000-0003-2716-4331
Jun Li http://orcid.org/0000-0001-9964-1657
Funding Agency and Grant Number
Funding Agency Grant Number
National Thirteen Five-year Great Science and Technology Project 2018ZX10725506-002
National Twelve Five-year Great Science and Technology Project 2012ZX10005-005
Corresponding Author Man Gong, MD, Associate Professor, Department of Integrative Medicine, 5th Medical Center of Chinese PLA General Hospital, No. 100, the 4th Ring Road, Beijing 100039, China. gongman302@163.com
Key Words Hepatitis B virus; Liver failure; Prognosis; Interleukin 6; /; /
Core Tip To triage and prognosticate the outcome is vital for management of patients with hepatitis B virus-associated acute-on-chronic liver failure (HBV-ACLF). Interleukin 6 (IL-6) is related with physiology and pathology of the liver. We found a high level of serum IL-6 was an independent risk factor for mortality in patients with HBV-ACLF. HBV-ACLF patients with high level of IL-6 showed high mortality, especially with persistent high level within 4 wk, indicating that IL-6 was an index of prognosis for HBV-ACLF.
Publish Date 2020-08-14 12:33
Citation Zhou C, Zhang N, He TT, Wang Y, Wang LF, Sun YQ, Jing J, Zhang JJ, Fu SN, Wang X, Liang XX, Li X, Gong M, Li J. High levels of serum interleukin-6 increase mortality of hepatitis B virus-associated acute-on-chronic liver failure. World J Gastroenterol 2020; 26(30): 4479-4488
URL https://www.wjgnet.com/1007-9327/full/v26/i30/4479.htm
DOI https://dx.doi.org/10.3748/wjg.v26.i30.4479
Full Article (PDF) WJG-26-4479.pdf
Full Article (Word) WJG-26-4479.docx
Manuscript File 56043-Review_WangTQ.docx
Answering Reviewers 56043-Answering reviewers.pdf
Audio Core Tip 56043-Audio core tip.mp3
Biostatistics Review Certificate 56043-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 56043-Conflict-of-interest statement.pdf
Copyright License Agreement 56043-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 56043-Grant application form(s).pdf
Signed Informed Consent Form(s) or Document(s) 56043-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 56043-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 56043-Language certificate.pdf
Supplementary Material 56043-Supplementary material.pdf
Peer-review Report 56043-Peer-review(s).pdf
Scientific Misconduct Check 56043-Scientific misconduct check.pdf
Scientific Editor Work List 56043-Scientific editor work list.pdf