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11/20/2020 4:04:17 AM | Browse: 14 | Download: 21
Publication Name World Journal of Gastroenterology
Manuscript ID 56930
Country/Territory Brazil
Received
2020-05-25 19:28
Peer-Review Started
2020-05-20 22:06
To Make the First Decision
Return for Revision
2020-07-29 04:12
Revised
2020-08-12 02:55
Second Decision
2020-09-30 08:52
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2020-10-01 05:14
Articles in Press
2020-10-01 05:14
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2020-11-12 02:13
Publish the Manuscript Online
2020-11-20 04:04
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Pharmacology and Pharmacy
Manuscript Type Basic Study
Article Title Antifungal activity and antidiarrheal activity via antimotility mechanisms of (-)-fenchone in experimental models
Manuscript Source Unsolicited Manuscript
All Author List Michelle Liz de Souza Pessoa, Leiliane Macena Oliveira Silva, Maria Elaine Cristina Araruna, Catarina Alves de Lima Serafim, Edvaldo Balbino Alves Júnior, Alessa Oliveira Silva, Matheus Marley Bezerra Pessoa, Hermes Diniz Neto, Edeltrudes de Oliveira Lima and Leônia Maria Batista
ORCID
Author(s) ORCID Number
Michelle Liz de Souza Pessoa http://orcid.org/0000-0003-4111-3258
Leiliane Macena Oliveira Silva http://orcid.org/0000-0002-3932-1464
Maria Elaine Cristina Araruna http://orcid.org/0000-0001-7317-7446
Catarina Alves de Lima Serafim http://orcid.org/0000-0002-2464-5840
Edvaldo Balbino Alves Júnior http://orcid.org/0000-0002-3311-1247
Alessa Oliveira Silva http://orcid.org/0000-0002-9573-3869
Matheus Marley Bezerra Pessoa http://orcid.org/0000-0002-4086-946X
Hermes Diniz Neto http://orcid.org/0000-0003-2878-1737
Edeltrudes de Oliveira Lima http://orcid.org/0000-0002-9547-0886
Leônia Maria Batista http://orcid.org/0000-0002-5001-2486
Funding Agency and Grant Number
Corresponding author Leônia Maria Batista, PharmD, Associate Professor, Professor, Postgraduate Program in Natural and Synthetic Bioactive Products, Universidade Federal da Paraiba, Cidade Universitária, s/n - Castelo Branco III, João Pessoa 58051-900, Brazil. leoniab@uol.com.br
Key Words (-)-Fenchone; Monoterpenes; Diarrhea; Motility; Antifungal;
Core Tip (-)-Fenchone is a bicyclic monoterpene present in essential oils of plant species, such as Foeniculum vulgare and Peumus boldus, used to treatment of gastrointestinal diseases. Diarrhea is a pathological condition characterized by an increase in three or more defecations in 24 h, being of multiple origins, whether infectious or not. In the search for new therapeutic alternatives, natural products, and medicinal plants are of great relevance. Many species of plants and their isolated compounds, including terpenes, have shown promising antidiarrheal and motility, based on this result, the monoterpene (-)-fenchone was selected for this study.
Publish Date 2020-11-20 04:04
Citation Pessoa MLS, Silva LMO, Araruna MEC, Serafim CAL, Alves Júnior EB, Silva AO, Pessoa MMB, Diniz Neto H, de Oliveira Lima E, Batista LM. Antifungal activity and antidiarrheal activity via antimotility mechanisms of (-)-fenchone in experimental models. World J Gastroenterol 2020; 26(43): 6795-6809
Url https://www.wjgnet.com/1007-9327/full/v26/i43/6795.htm
DOI https://dx.doi.org/10.3748/wjg.v26.i43.6795
Full Article (PDF) WJG-26-6795.pdf
Full Article (Word) WJG-26-6795.docx
Manuscript File 56930_Auto_Edited.docx
Answering Reviewers 56930-Answering reviewers.pdf
Audio Core Tip 56930-Audio core tip.mp4
Biostatistics Review Certificate 56930-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 56930-Conflict-of-interest statement.pdf
Copyright License Agreement 56930-Copyright license agreement.pdf
Institutional Animal Care and Use Committee Approval Form or Document 56930-Institutional animal care and use committee statement.pdf
Institutional Review Board Approval Form or Document 56930-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 56930-Language certificate.pdf
Peer-review Report 56930-Peer-review(s).pdf
Scientific Misconduct Check 56930-Bing-Yan JP-1.png
Scientific Misconduct Check 56930-Scientific misconduct check.pdf
Scientific Editor Work List 56930-Scientific editor work list.pdf