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9/22/2020 6:23:06 AM | Browse: 31 | Download: 50
Publication Name World Journal of Stem Cells
Manuscript ID 57521
Country/Territory Poland
Received
2020-06-12 11:10
Peer-Review Started
2020-06-12 11:11
To Make the First Decision
Return for Revision
2020-07-30 23:32
Revised
2020-08-24 10:12
Second Decision
2020-09-01 11:08
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2020-09-01 20:42
Articles in Press
2020-09-01 20:42
Publication Fee Transferred
Edit the Manuscript by Language Editor
2020-09-06 01:28
Typeset the Manuscript
2020-09-18 17:42
Publish the Manuscript Online
2020-09-22 06:23
ISSN 1948-0210 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Respiratory System
Manuscript Type Minireviews
Article Title Perspectives on mesenchymal stem/progenitor cells and their derivates as potential therapies for lung damage caused by COVID-19
Manuscript Source Invited Manuscript
All Author List Aleksandra Klimczak
ORCID
Author(s) ORCID Number
Aleksandra Klimczak http://orcid.org/0000-0001-6590-4420
Funding Agency and Grant Number
Corresponding Author Aleksandra Klimczak, DSc, PhD, Full Professor, Laboratory of Biology of Stem and Neoplastic Cells, Hirszfeld Institute of Immunology and Experimental Therapy Polish Academy of Sciences, Rudolfa Weigla 12, Wrocław 53-114, Poland. aleksandra.klimczak@hirszfeld.pl
Key Words Mesenchymal stem cells; Stem/progenitor cells; Lung damage; Mesenchymal stem cell secretome; COVID-19 disease; COVID-19 pneumonia
Core Tip The new severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has reached pandemic proportions, developing the coronavirus disease (COVID-19), which leads to the severe pneumonia. The lungs are the primary organ affected by SARS-CoV-2, with a very slow turnover for renewal. SARS-CoV-2 enters the lungs and induces immune response with cytokine storm and subsequent organ dysfunction. To date, there is no effective antiviral therapy for COVID-19. Cell-based therapy involving mesenchymal stem cells (MSCs) and/or their secretome is considered as a supportive therapy for critically ill COVID-19 patients. MSCs can regenerate severely injured respiratory tract cells through their trophic, anti-inflammatory, and immunomodulatory properties.
Publish Date 2020-09-22 06:23
Citation Klimczak A. Perspectives on mesenchymal stem/progenitor cells and their derivates as potential therapy in lung damage caused by COVID-19. World J Stem Cells 2020; 12(9): 1013-1022
Url https://www.wjgnet.com/1948-0210/full/v12/i9/1013.htm
DOI https://dx.doi.org/10.4252/wjsc.v12.i9.1013
Full Article (PDF) WJSC-12-1013.pdf
Full Article (Word) WJSC-12-1013.docx
Manuscript File 57521-Review-Filipodia.docx
Answering Reviewers 57521-Answering reviewers.pdf
Audio Core Tip 57521-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 57521-Conflict-of-interest statement.pdf
Copyright License Agreement 57521-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate 57521-Language certificate.pdf
Peer-review Report 57521-Peer-review(s).pdf
Scientific Misconduct Check 57521-Scientific misconduct check.pdf
Scientific Editor Work List 57521-Scientific editor work list.pdf