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12/13/2020 5:45:32 AM | Browse: 495 | Download: 576
Publication Name World Journal of Diabetes
Manuscript ID 58157
Country United States
Received
2020-07-09 18:03
Peer-Review Started
2020-07-09 18:04
To Make the First Decision
Return for Revision
2020-10-06 16:40
Revised
2020-10-20 03:46
Second Decision
2020-11-11 09:48
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2020-11-12 17:02
Articles in Press
2020-11-12 17:02
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2020-12-02 05:56
Publish the Manuscript Online
2020-12-13 05:45
ISSN 1948-9358 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Medicine, Research & Experimental
Manuscript Type Minireviews
Article Title SX-fraction: Promise for novel treatment of type 2 diabetes
Manuscript Source Invited Manuscript
All Author List Sensuke Konno
ORCID
Author(s) ORCID Number
Sensuke Konno http://orcid.org/0000-0003-2690-2507
Funding Agency and Grant Number
Corresponding Author Sensuke Konno, PhD, Associate Professor, Department of Urology, New York Medical College, BSB Room A03, Valhalla, NY 10595, United States. sensuke_konno@nymc.edu
Key Words SX-fraction; Diabetes; Anti-diabetic; Hypoglycemic; Insulin signal pathway;
Core Tip We have been searching for a natural agent capable of controlling diabetic conditions in patients with type 2 diabetes for years. We then came across “SX-fraction (SXF)”, isolated from maitake mushroom (Grifola frondorsa), with anti-diabetic and hypoglycemic activities. In this short review, we chronologically described several key studies of SXF such as animal studies using diabetic mice (to demonstrate anti-diabetic activity), limited clinical studies on volunteer patients with type 2 diabetes (to show hypoglycemic activity), and in vitro study using skeletal muscle cells (to elucidate the hypoglycemic mechanism). After all, SXF appears to be a natural, safe, effective agent for treatment of patients with type 2 diabetes, although more (clinical) studies are yet required for confirmation.
Publish Date 2020-12-13 05:45
Citation Konno S. SX-fraction: Promise for novel treatment of type 2 diabetes. World J Diabetes 2020; 11(12): 572-583
URL https://www.wjgnet.com/1948-9358/full/v11/i12/572.htm
DOI https://dx.doi.org/10.4239/wjd.v11.i12.572
Full Article (PDF) WJD-11-572.pdf
Full Article (Word) WJD-11-572.docx
Manuscript File 58157_Auto_Edited.docx
Answering Reviewers 58157-Answering reviewers.pdf
Audio Core Tip 58157-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 58157-Conflict-of-interest statement.pdf
Copyright License Agreement 58157-Copyright license agreement.pdf
Peer-review Report 58157-Peer-review(s).pdf
Scientific Misconduct Check 58157-Scientific misconduct check.pdf
Scientific Editor Work List 58157-Scientific editor work list.pdf