Publication Name	World Journal of Hepatology
Manuscript ID	6055
Country	Türkiye

Received	2013-10-01 17:38
Peer-Review Started	2013-10-01 19:25
To Make the First Decision	2013-10-14 14:14
Return for Revision	2013-10-16 14:22
Revised
Second Decision	2013-12-10 16:34
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2013-12-11 09:56
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor	2013-12-16 15:25
Typeset the Manuscript	2014-01-19 12:19
Publish the Manuscript Online	2014-01-26 15:15

ISSN	1948-5182 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Review
Article Title	Fatty liver in childhood
Manuscript Source	Invited Manuscript
All Author List	Yesim Ozturk and Ozlem Bekem Soylu
Funding Agency and Grant Number
Corresponding Author	Yesim Ozturk, MD, PhD, Professor, Department of Pediatrics, Division of Pediatric Gastroenterology, Dokuz Eylul University School of Medicine, Inciralti, Cumhuriyet Blv No.144, 35340 İzmir, Turkey. yesimzaferozturk@gmail.com
Key Words	Nonalcoholic fatty liver disease; Nonalcoholic steatohepatitis; Children; Obesity; Metabolic syndrome; Insulin resistance; Chronic liver disease
Core Tip	Nonalcoholic fatty liver disease (NAFLD) consists of steatosis in liver, steatohepatitis and cirrhosis. Histological type 2 pattern (macrovesicular steatosis with portal inflammation and/or fibrosis, generally without evidence of cellular injury or lobular inflammation) is seen differently in children than in adults. The most important risk factors are obesity and insulin resistance, as well as gender, ethnicity, genetic predisposition and some medical problems. Progression to cirrhosis in children is rare but possible. NAFLD does not have a proven treatment. Losing weight and increasing physical activity provide improvement in histological and biochemical findings in fatty liver. Drugs are used in specific situations. More research is needed for drug therapy.
Publish Date	2014-01-26 15:15
Citation	Ozturk Y, Soylu OB. Fatty liver in childhood. World J Hepatol 2014; 6(1): 33-40
URL	http://www.wjgnet.com/1948-5182/full/v6/i1/33.htm
DOI	http://dx.doi.org/10.4254/wjh.v6.i1.33

Full Article (PDF)	WJH-6-33.pdf
Full Article (Word)	WJH-6-33.doc
Manuscript File	6055-Review.docx
Answering Reviewers	6055-Answering reviewers.pdf
Copyright License Agreement	6055-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	6055-Language certificate.pdf
Peer-review Report	6055-Peer review(s).pdf
Scientific Editor Work List	6055-Scientific editor work list.doc