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9/10/2014 6:38:00 PM | Browse: 756 | Download: 695
Publication Name World Journal of Hepatology
Manuscript ID 6055
Country/Territory Türkiye
Received
2013-10-01 17:38
Peer-Review Started
2013-10-01 19:25
To Make the First Decision
2013-10-14 14:14
Return for Revision
2013-10-16 14:22
Revised
Second Decision
2013-12-10 16:34
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2013-12-11 09:56
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
2013-12-16 15:25
Typeset the Manuscript
2014-01-19 12:19
Publish the Manuscript Online
2014-01-26 15:15
ISSN 1948-5182 (online)
Open Access
Copyright
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Review
Article Title Fatty liver in childhood
Manuscript Source Invited Manuscript
All Author List Yesim Ozturk and Ozlem Bekem Soylu
Funding Agency and Grant Number
Corresponding Author Yesim Ozturk, MD, PhD, Professor, Department of Pediatrics, Division of Pediatric Gastroenterology, Dokuz Eylul University School of Medicine, Inciralti, Cumhuriyet Blv No.144, 35340 İzmir, Turkey. yesimzaferozturk@gmail.com
Key Words Nonalcoholic fatty liver disease; Nonalcoholic steatohepatitis; Children; Obesity; Metabolic syndrome; Insulin resistance; Chronic liver disease
Core Tip Nonalcoholic fatty liver disease (NAFLD) consists of steatosis in liver, steatohepatitis and cirrhosis. Histological type 2 pattern (macrovesicular steatosis with portal inflammation and/or fibrosis, generally without evidence of cellular injury or lobular inflammation) is seen differently in children than in adults. The most important risk factors are obesity and insulin resistance, as well as gender, ethnicity, genetic predisposition and some medical problems. Progression to cirrhosis in children is rare but possible. NAFLD does not have a proven treatment. Losing weight and increasing physical activity provide improvement in histological and biochemical findings in fatty liver. Drugs are used in specific situations. More research is needed for drug therapy.
Publish Date 2014-01-26 15:15
Citation Ozturk Y, Soylu OB. Fatty liver in childhood. World J Hepatol 2014; 6(1): 33-40
URL http://www.wjgnet.com/1948-5182/full/v6/i1/33.htm
DOI http://dx.doi.org/10.4254/wjh.v6.i1.33
Full Article (PDF) WJH-6-33.pdf
Full Article (Word) WJH-6-33.doc
Manuscript File 6055-Review.docx
Answering Reviewers 6055-Answering reviewers.pdf
Copyright License Agreement 6055-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate 6055-Language certificate.pdf
Peer-review Report 6055-Peer review(s).pdf
Scientific Editor Work List 6055-Scientific editor work list.doc