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3/1/2021 3:51:08 AM | Browse: 234 | Download: 363
Publication Name World Journal of Clinical Cases
Manuscript ID 60707
Country/Territory China
2020-11-10 05:35
Peer-Review Started
2020-11-10 05:35
To Make the First Decision
Return for Revision
2020-12-08 07:03
2020-12-13 16:09
Second Decision
2020-12-22 13:12
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2020-12-23 21:01
Articles in Press
2020-12-23 21:01
Publication Fee Transferred
Edit the Manuscript by Language Editor
2021-01-18 17:11
Typeset the Manuscript
2021-02-24 01:10
Publish the Manuscript Online
2021-03-01 03:51
ISSN 2307-8960 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Infectious Diseases
Manuscript Type Observational Study
Article Title Elevated soluble 4-1BB is associated with serum markers of hepatitis B virus in patients with chronic hepatitis B
Manuscript Source Unsolicited Manuscript
All Author List Meng-Ru Zhan, Xiu-Zhu Gao, Chang Wang, Fei Peng, Xiao-Mei Wang, Hong-Qin Xu and Jun-Qi Niu
Author(s) ORCID Number
Meng-Ru Zhan http://orcid.org/0000-0002-2419-6859
Xiu-Zhu Gao http://orcid.org/0000-0001-6310-1456
Chang Wang http://orcid.org/0000-0002-0003-1865
Fei Peng http://orcid.org/0000-0002-5446-9854
Xiao-Mei Wang http://orcid.org/0000-0003-2606-4013
Hong-Qin Xu http://orcid.org/0000-0002-7022-7732
Jun-Qi Niu http://orcid.org/0000-0001-5415-2024
Funding Agency and Grant Number
Funding Agency Grant Number
Chinese Foundation for Hepatitis Prevention and Control—Tian-Qing Liver Disease Research Fund Subject TQGB20200118
Corresponding Author Jun-Qi Niu, MD, PhD, Academic Research, Dean, Director, Doctor, Professor, Research Scientist, Department of Hepatology, The First Hospital of Jilin University, No. 1 Xinmin Street, Changchun 130021, Jilin Province, China. junqiniu@jlu.edu.cn
Key Words Hepatitis B virus; Hepatitis B; Chronic; 4-1BB; Soluble 4-1BB; Hepatitis B virus serum marker
Core Tip Over 240 million people all round the world are chronically infected with hepatitis B virus, resulting in > 1 million deaths per year. Previous studies have suggested that the costimulatory molecule 4-1BB, plays pivotal roles in regulating immunity during chronic viral infection. However, up to now, there is no study about 4-1BB expression in chronic hepatitis B to clarify the role of 4-1BB in the process of chronic hepatitis B clearly. Here, we report our comprehensive study on the expression levels of soluble 4-1BB in plasma and 4-1BB mRNA in peripheral blood mononuclear cells to further explain it.
Publish Date 2021-03-01 03:51
Citation Zhan MR, Gao XZ, Wang C, Peng F, Wang XM, Xu HQ, Niu JQ. Elevated soluble 4-1BB is associated with serum markers of hepatitis B virus in patients with chronic hepatitis B. World J Clin Cases 2021; 9(7): 1619-1630
URL https://www.wjgnet.com/2307-8960/full/v9/i7/1619.htm
DOI https://dx.doi.org/10.12998/wjcc.v9.i7.1619
Full Article (PDF) WJCC-9-1619.pdf
Full Article (Word) WJCC-9-1619.docx
Manuscript File 60707-Review-Filipodia_CL.docx
Answering Reviewers 60707-Answering reviewers.pdf
Audio Core Tip 60707-Audio core tip.mp3
Biostatistics Review Certificate 60707-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 60707-Conflict-of-interest statement.pdf
Copyright License Agreement 60707-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 60707-Grant application form(s).pdf
Signed Informed Consent Form(s) or Document(s) 60707-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 60707-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 60707-Language certificate.pdf
Peer-review Report 60707-Peer-review(s).pdf
Scientific Misconduct Check 60707-Bing-Fan JR-1.png
Scientific Misconduct Check 60707-Scientific misconduct check.pdf
Scientific Editor Work List 60707-Scientific editor work list.pdf