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Articles Published Processes
6/11/2021 9:22:17 AM | Browse: 322 | Download: 721
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Received |
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2020-12-11 08:52 |
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Peer-Review Started |
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2020-12-11 08:54 |
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To Make the First Decision |
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Return for Revision |
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2021-01-19 09:38 |
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Revised |
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2021-01-26 11:20 |
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Second Decision |
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2021-02-25 13:09 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2021-02-26 18:48 |
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Articles in Press |
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2021-02-26 18:48 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2021-04-28 03:28 |
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Typeset the Manuscript |
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2021-06-03 07:11 |
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Publish the Manuscript Online |
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2021-06-11 09:22 |
| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Medicine, Research & Experimental |
| Manuscript Type |
Basic Study |
| Article Title |
Identification of the circRNA-miRNA-mRNA regulatory network and its prognostic effect in colorectal cancer
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Teng-Fei Yin, Dong-Yan Zhao, Yuan-Chen Zhou, Qian-Qian Wang and Shu-Kun Yao |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Key Development Plan for Precision Medicine Research |
2017YFC0910002 |
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| Corresponding Author |
Shu-Kun Yao, MD, PhD, Professor, Department of Gastroenterology, China-Japan Friendship Hospital, No. 2 Yinghua East Road, Chaoyang District, Beijing 100029, China. shukunyao@126.com |
| Key Words |
CircRNA; MiRNA; Network; Colorectal cancer; Prognosis; Biomarkers |
| Core Tip |
The biological functions of circRNA and miRNA interactions and their potential as noninvasive biomarkers have not been well elucidated in colorectal cancer (CRC). In this study, we constructed a circRNA-miRNA-mRNA regulatory network with 19 circRNAs, 13 miRNAs and 28 mRNAs. GO and KEGG analyses indicated several signaling pathways probably involved in tumorigenesis. After being combined with survival analysis, a prognostic subnetwork was constructed including 5 circRNAs, 3 miRNAs and 3 mRNAs, which may represent novel diagnostic and prognostic candidate biomarkers, as well as therapeutic targets of CRC. |
| Publish Date |
2021-06-11 09:22 |
| Citation |
Yin TF, Zhao DY, Zhou YC, Wang QQ, Yao SK. Identification of the circRNA-miRNA-mRNA regulatory network and its prognostic effect in colorectal cancer. World J Clin Cases 2021; 9(18): 4520-4541 |
| URL |
https://www.wjgnet.com/2307-8960/full/v9/i18/4520.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v9.i18.4520 |
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