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4/9/2021 8:11:25 AM | Browse: 39 | Download: 56
Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 61832
Country/Territory China
2020-12-21 09:35
Peer-Review Started
2020-12-21 09:38
To Make the First Decision
Return for Revision
2021-01-11 05:00
2021-01-14 16:24
Second Decision
2021-02-24 06:30
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2021-03-11 03:08
Articles in Press
2021-03-11 03:08
Publication Fee Transferred
Edit the Manuscript by Language Editor
2021-03-19 01:38
Typeset the Manuscript
2021-03-25 01:18
Publish the Manuscript Online
2021-04-09 08:11
ISSN 1948-5204 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology and Hepatology
Manuscript Type Review
Article Title Early diagnosis and therapeutic strategies for hepatocellular carcinoma: From bench to bedside
Manuscript Source Invited Manuscript
All Author List Ming-Cheng Guan, Ming-Da Wang, Si-Yu Liu, Wei Ouyang, Lei Liang, Timothy M Pawlik, Qiu-Ran Xu, Dong-Sheng Huang, Feng Shen, Hong Zhu and Tian Yang
Author(s) ORCID Number
Ming-Cheng Guan http://orcid.org/0000-0002-7845-3689
Ming-Da Wang http://orcid.org/0000-0001-5372-9768
Si-Yu Liu http://orcid.org/0000-0001-9614-5674
Wei Ouyang http://orcid.org/0000-0003-2750-7322
Lei Liang http://orcid.org/0000-0003-3294-2978
Timothy M Pawlik http://orcid.org/0000-0002-8432-9086
Qiu-Ran Xu http://orcid.org/0000-0002-4545-1644
Dong-Sheng Huang http://orcid.org/0000-0001-7276-6054
Feng Shen http://orcid.org/0000-0001-7040-5044
Hong Zhu http://orcid.org/0000-0001-7502-278X
Tian Yang http://orcid.org/0000-0003-1544-0976
Funding Agency and Grant Number
Funding Agency Grant Number
National Natural Science Foundation of China (General Program) 81972726
Corresponding Author Tian Yang, MD, Doctor, Department of Hepatobiliary Surgery, Eastern Hepatobiliary Surgery Hospital (Navy Medical University), Second Military Medical University, No. 225, Changhai Road, Shanghai 200438, China. yangtian6666@hotmail.com
Key Words Hepatocellular carcinoma; Early detection; Biomarker; Therapeutic strategies; Immunotherapeutic innovations
Core Tip Long-term survival relies upon early diagnosis and timely treatment for patients with hepatocellular carcinoma. In this review, an update on the non-invasive early molecular detection and therapeutic strategies associated with hepatocellular carcinoma is discussed, focusing on omics-related biomarkers (e.g., proteins, metabolites, circulating tumor deoxyribonucleic acid, circulating non-coding ribonucleic acid), locoregional and systemic therapies for treating different stage hepatocellular carcinoma, as well as potential immunotherapeutic innovations (e.g., adoptive cell transfer therapy).
Publish Date 2021-04-09 08:11
Citation Guan MC, Wang MD, Liu SY, Ouyang W, Liang L, Pawlik TM, Xu QR, Huang DS, Shen F, Zhu H, Yang T. Early diagnosis and therapeutic strategies for hepatocellular carcinoma: From bench to bedside. World J Gastrointest Oncol 2021; 13(4): 197-215
URL https://www.wjgnet.com/1948-5204/full/v13/i4/197.htm
DOI https://dx.doi.org/10.4251/wjgo.v13.i4.197
Full Article (PDF) WJGO-13-197.pdf
Full Article (Word) WJGO-13-197.docx
Manuscript File 61832-Review-FilipodiaCL.docx
Answering Reviewers 61832-Answering reviewers.pdf
Audio Core Tip 61832-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 61832-Conflict-of-interest statement.pdf
Copyright License Agreement 61832-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 61832-Grant application form(s).pdf
Non-Native Speakers of English Editing Certificate 61832-Language certificate.pdf
Peer-review Report 61832-Peer-review(s).pdf
Scientific Misconduct Check 61832-Scientific misconduct check.pdf
Scientific Editor Work List 61832-Scientific editor work list.pdf