| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Review |
| Article Title |
Early diagnosis and therapeutic strategies for hepatocellular carcinoma: From bench to bedside
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Ming-Cheng Guan, Ming-Da Wang, Si-Yu Liu, Wei Ouyang, Lei Liang, Timothy M Pawlik, Qiu-Ran Xu, Dong-Sheng Huang, Feng Shen, Hong Zhu and Tian Yang |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China (General Program) |
81972726 |
|
| Corresponding Author |
Tian Yang, MD, Doctor, Doctor, Department of Hepatobiliary Surgery, Eastern Hepatobiliary Surgery Hospital (Navy Medical University), Second Military Medical University, No. 225, Changhai Road, Shanghai 200438, China. yangtian6666@hotmail.com |
| Key Words |
Hepatocellular carcinoma; Early detection; Biomarker; Therapeutic strategies; Immunotherapeutic innovations |
| Core Tip |
Long-term survival relies upon early diagnosis and timely treatment for patients with hepatocellular carcinoma. In this review, an update on the non-invasive early molecular detection and therapeutic strategies associated with hepatocellular carcinoma is discussed, focusing on omics-related biomarkers (e.g., proteins, metabolites, circulating tumor deoxyribonucleic acid, circulating non-coding ribonucleic acid), locoregional and systemic therapies for treating different stage hepatocellular carcinoma, as well as potential immunotherapeutic innovations (e.g., adoptive cell transfer therapy). |
| Publish Date |
2021-04-09 08:11 |
| Citation |
Guan MC, Wang MD, Liu SY, Ouyang W, Liang L, Pawlik TM, Xu QR, Huang DS, Shen F, Zhu H, Yang T. Early diagnosis and therapeutic strategies for hepatocellular carcinoma: From bench to bedside. World J Gastrointest Oncol 2021; 13(4): 197-215 |
| URL |
https://www.wjgnet.com/1948-5204/full/v13/i4/197.htm |
| DOI |
https://dx.doi.org/10.4251/wjgo.v13.i4.197 |
