| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Case Report |
| Article Title |
Conversion hepatectomy for hepatocellular carcinoma with main portal vein tumour thrombus after lenvatinib treatment: A case report
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Kazuhiro Takahashi, Jaejeong Kim, Amane Takahashi, Shinji Hashimoto, Manami Doi, Kinji Furuya, Ryosuke Hashimoto, Yohei Owada, Koichi Ogawa, Yusuke Ohara, Yoshimasa Akashi, Katsuji Hisakura, Tsuyoshi Enomoto, Osamu Shimomura, Masayuki Noguchi and Tatsuya Oda |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Kazuhiro Takahashi, MD, PhD, Surgeon, Department of Gastrointestinal and Hepatobiliary Pancreatic Surgery, University of Tsukuba, 1-1-1 Tennoudai, Tsukuba 3058575, Ibaraki, Japan. kazu1123@md.tsukuba.ac.jp |
| Key Words |
Hepatocellular carcinoma; Lenvatinib; Portal vein tumour thrombus; Conversion hepatectomy; Case report |
| Core Tip |
Patients with hepatocellular carcinoma (HCC) with portal vein tumour thrombus demonstrate an aggressive disease course, decreased liver function reserve, and higher recurrence rates after treatment. Clinical practice guidelines recommend systemic therapy as the first-line option for HCC with portal invasion. However, to achieve longer survival in these patients, the treatment strategy should be concluded with removal of the tumour. We report the first case of HCC with main portal vein tumour thrombus, in which radical conversion hepatectomy was successfully performed after lenvatinib treatment. Lenvatinib has several strengths that validate its use for targeting conversion hepatectomy for unresectable HCC. |
| Publish Date |
2021-03-20 02:13 |
| Citation |
Takahashi K, Kim J, Takahashi A, Hashimoto S, Doi M, Furuya K, Hashimoto R, Owada Y, Ogawa K, Ohara Y, Akashi Y, Hisakura K, Enomoto T, Shimomura O, Noguchi M, Oda T. Conversion hepatectomy for hepatocellular carcinoma with main portal vein tumour thrombus after lenvatinib treatment: A case report. World J Hepatol 2021; 13(3): 384-392 |
| URL |
https://www.wjgnet.com/1948-5182/full/v13/i3/384.htm |
| DOI |
https://dx.doi.org/10.4254/wjh.v13.i3.384 |
