Publication Name	World Journal of Stem Cells
Manuscript ID	62844
Country	United States

Received	2021-01-19 16:10
Peer-Review Started	2021-01-19 16:11
To Make the First Decision
Return for Revision	2021-02-13 23:59
Revised	2021-02-22 19:17
Second Decision	2021-03-26 09:32
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2021-03-30 02:29
Articles in Press	2021-03-30 02:29
Publication Fee Transferred
Edit the Manuscript by Language Editor	2021-04-05 20:57
Typeset the Manuscript	2021-04-20 00:51
Publish the Manuscript Online	2021-04-22 10:31

ISSN	1948-0210 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Research & Experimental Medicine
Manuscript Type	Review
Article Title	Calcium channels and their role in regenerative medicine
Manuscript Source	Invited Manuscript
All Author List	Nassem Ahamad and Brij B Singh
ORCID	Author(s) ORCID Number Nassem Ahamad http://orcid.org/0000-0003-0535-5667 Brij B Singh http://orcid.org/0000-0003-0535-5997
Funding Agency and Grant Number	Funding Agency Grant Number National Institute of Dental & Craniofacial Research 1R21DE028265-01A1
Corresponding Author	Brij B Singh, PhD, Dean, Full Professor, School of Dentistry, UT Health Science Center San Antonio, 7703, Floyd Curl Dr., San Antonio, TX 78257, United States. singhbb@uthscsa.edu
Key Words	Ca2+ signaling; Ca2+ channels; Transient receptor potential channel 1/Orai1 stem cells; Regenerative medicine; Stem cells
Core Tip	Regenerative medicine has the potential to replace damaged tissues. Stem cells provide new hope for regenerative therapy as they have indefinite self-renewable capability and can differentiate into all cell types. Stem cells could be obtained from several both exogenous and endogenous sources. Moreover, stem cells migrate towards the damaged organs, however, signaling molecules/factors that allows them to move to damaged organs and facilitate repair are not fully identified. Ca2+ signaling is critical for appropriate functioning of stem cells. Importantly, Ca2+ signaling is highly adaptable, and how it modulates stem cell function and its regenerative capacity is discussed in this article.
Publish Date	2021-04-22 10:31
Citation	Ahamad N, Singh BB. Calcium channels and their role in regenerative medicine. World J Stem Cells 2021; 13(4): 260-280
URL	https://www.wjgnet.com/1948-0210/full/v13/i4/260.htm
DOI	https://dx.doi.org/10.4252/wjsc.v13.i4.260

Full Article (PDF)	WJSC-13-260.pdf
Full Article (Word)	WJSC-13-260.docx
Manuscript File	62844-Review-FilipodiaCL.docx
Answering Reviewers	62844-Answering reviewers.pdf
Audio Core Tip	62844-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	62844-Conflict-of-interest statement.pdf
Copyright License Agreement	62844-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	62844-Grant application form(s).pdf
Peer-review Report	62844-Peer-review(s).pdf
Scientific Misconduct Check	62844-Bing-Wang JL-1.jpg
Scientific Misconduct Check	62844-Scientific misconduct check.pdf
Scientific Editor Work List	62844-Scientific editor work list.pdf