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Articles Published Processes
7/23/2021 1:30:22 PM | Browse: 453 | Download: 826
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Received |
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2021-01-29 11:14 |
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Peer-Review Started |
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2021-01-29 11:32 |
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To Make the First Decision |
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Return for Revision |
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2021-02-28 05:34 |
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Revised |
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2021-04-29 15:55 |
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Second Decision |
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2021-06-25 13:50 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2021-06-25 14:16 |
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Articles in Press |
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2021-06-25 14:16 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2021-07-01 05:20 |
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Typeset the Manuscript |
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2021-07-22 05:52 |
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Publish the Manuscript Online |
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2021-07-23 13:30 |
| ISSN |
1948-0210 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Orthopedics |
| Manuscript Type |
Case Report |
| Article Title |
First immunohistochemical evidence of human tendon repair following stem cell injection: A case report and review of literature
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Eckhard Alt, Ralf Rothoerl, Matthias Hoppert, Hans-Georg Frank, Tobias Wuerfel, Christopher Alt and Christoph Schmitz |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Eckhard Alt, MD, Professor, Chairman of the Board, Isarklinikum Muenchen, Sonnenstr. 24-26, Munich 80331, Germany. e.alt@biomed-science.com |
| Key Words |
Stem cells; Partial-thickness rotator cuff tear; Tendon regeneration; Adipose derived regenerative cells; Cell-based therapy at Point of Care; Case report |
| Core Tip |
Current treatment options for partial-thickness rotator cuff tear do not offer the potential to form new tendon tissue. The results of this study suggest, for the first time, that treating an injured human supraspinatus tendon with fresh, uncultured, autologous, adipose derived regenerative cells prepared at the point of care enables regenerative healing of an injured tendon, as evidenced by comprehensive immunohistochemical analysis of biopsy taken from the patient’s tendon 2.5 mo post treatment. Regenerative healing without scar formation has previously been attributed only to fetal tendon development. |
| Publish Date |
2021-07-23 13:30 |
| Citation |
Alt E, Rothoerl R, Hoppert M, Frank HG, Wuerfel T, Alt C, Schmitz C. First immunohistochemical evidence of human tendon repair following stem cell injection: A case report and review of literature. World J Stem Cells 2021; 13(7): 944-970 |
| URL |
https://www.wjgnet.com/1948-0210/full/v13/i7/944.htm |
| DOI |
https://dx.doi.org/10.4252/wjsc.v13.i7.944 |
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