Category |
Gastroenterology & Hepatology |
Manuscript Type |
Autobiography |
Article Title |
Propensity score analysis demonstrated the prognostic advantage of anatomical liver resection in hepatocellular carcinoma
|
Manuscript Source |
Invited Manuscript |
All Author List |
Masayuki Ishii, Toru Mizuguchi, Masaki Kawamoto, Makoto Meguro, Shigenori Ota, Toshihiko Nishidate, Kenji Okita, Yasutohsi Kimura, Thomas T Hui and Koichi Hirata |
Funding Agency and Grant Number |
Funding Agency |
Grant Number |
Ministry of Education, Culture, Sports, Science, and Technology |
23591993 |
Yuasa Memorial Foundation |
|
|
Corresponding Author |
Toru Mizuguchi, MD, PhD, Department of Surgery, Surgical Oncology and Science, Sapporo Medical University School of Medicine, S-1, W-16, Chuo-Ku, Sapporo 060-8543, Hokkaido, Japan. tmizu@sapmed.ac.jp |
Key Words |
Anatomical liver resection; Propensity score analysis; Hepatocellular carcinoma |
Core Tip |
The aim of this study was to compare the prognostic advantage of hepatocellular carcinoma (HCC) patients that underwent anatomic liver resection (AR) or non-anatomic liver resection (NAR) using propensity score-matched populations. Consecutive 268 HCC patients were enrolled and 44 patients from each group were matched using logistic multivariate analysis followed by propensity score analysis. The overall survival of the AR group was significantly longer than that of the NAR group after propensity matching. Vascular invasion and the hepatocyte growth factor level were subsequently found to be independent prognostic factors. AR conveys a survival advantage over NAR in specific subpopulations of HCC patients. |
Publish Date |
2014-03-27 12:04 |
Citation |
Ishii M, Mizuguchi T, Kawamoto M, Meguro M, Ota S, Nishidate T, Okita K, Kimura Y, Hui TT, Hirata K. Propensity score analysis demonstrated the prognostic advantage of anatomical liver resection in hepatocellular carcinoma. World J Gastroenterol 2014; 20(12): 3335-3342 |
URL |
http://www.wjgnet.com/1007-9327/full/v20/i12/3335.htm |
DOI |
http://dx.doi.org/10.3748/wjg.v20.i12.3335 |