Publication Name	World Journal of Gastroenterology
Manuscript ID	65674
Country	Spain

Received	2021-03-16 17:58
Peer-Review Started	2021-03-16 18:06
To Make the First Decision
Return for Revision	2021-05-01 04:47
Revised	2021-05-10 22:10
Second Decision	2021-09-03 03:06
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2021-09-03 06:58
Articles in Press	2021-09-03 06:58
Publication Fee Transferred
Edit the Manuscript by Language Editor	2021-09-14 00:51
Typeset the Manuscript	2021-10-18 05:53
Publish the Manuscript Online	2021-10-20 07:18

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Editorial
Article Title	Importance of BRCA mutation in the current treatment of pancreatic cancer beyond maintenance
Manuscript Source	Invited Manuscript
All Author List	Joaquina Martínez-Galán, Isabel Rodriguez and Octavio Caba
ORCID	Author(s) ORCID Number Joaquina Martínez-Galán http://orcid.org/0000-0002-6814-2748 Isabel Rodriguez http://orcid.org/0000-0003-4292-8731 Octavio Caba http://orcid.org/0000-0003-3426-8294
Funding Agency and Grant Number	Funding Agency Grant Number Junta de Andalucía PC-0498-2017 Junta de Andalucía PC-0549-2017
Corresponding Author	Octavio Caba, PhD, Professor, Institute of Biopathology and Regenerative Medicine (IBIMER), University of Granada, Avenida del Conocimiento s/n, Granada 18016, Spain. ocaba@ugr.es
Key Words	Pancreatic cancer; Treatment; BRCA; Mutation; Poly(ADP-ribose) polymerase inhibitor; Maintenance
Core Tip	Pancreatic cancer remains one of the most lethal malignant neoplasms, and available treatments have several limitations. Genetic studies are not currently recommended to support treatment selection. However, BRCA gene mutation has been associated with superior survival outcomes in patients treated with platinum-based chemotherapy. Hence, it appears appropriate to consider the BRCA gene status of patients with this cancer among clinical criteria for the selection of first-line chemotherapy regimen.
Publish Date	2021-10-20 07:18
Citation	Martínez-Galán J, Rodriguez I, Caba O. Importance of BRCA mutation in the current treatment of pancreatic cancer beyond maintenance. World J Gastroenterol 2021; 27(39): 6515-6521
URL	https://www.wjgnet.com/1007-9327/full/v27/i39/6515.htm
DOI	https://dx.doi.org/10.3748/wjg.v27.i39.6515

Full Article (PDF)	WJG-27-6515.pdf
Full Article (Word)	WJG-27-6515.docx
Manuscript File	65674-Review-Filipodia.docx
Answering Reviewers	65674-Answering reviewers.pdf
Audio Core Tip	65674-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	65674-Conflict-of-interest statement.pdf
Copyright License Agreement	65674-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	65674-Grant application form(s).pdf
Non-Native Speakers of English Editing Certificate	65674-Language certificate.pdf
Peer-review Report	65674-Peer-review(s).pdf
Scientific Misconduct Check	65674-Bing-Fan JR-2.png
Scientific Misconduct Check	65674-Scientific misconduct check.pdf
Scientific Editor Work List	65674-Scientific editor work list.pdf