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11/24/2021 9:54:22 AM | Browse: 16 | Download: 14
Publication Name World Journal of Hepatology
Manuscript ID 67173
Country/Territory Egypt
Received
2021-04-16 21:19
Peer-Review Started
2021-04-16 21:22
To Make the First Decision
Return for Revision
2021-06-23 08:16
Revised
2021-07-02 00:20
Second Decision
2021-09-01 02:13
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2021-09-01 09:37
Articles in Press
2021-09-01 09:37
Publication Fee Transferred
Edit the Manuscript by Language Editor
2021-09-09 00:52
Typeset the Manuscript
2021-11-18 03:34
Publish the Manuscript Online
2021-11-24 09:54
ISSN 1948-5182 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology and Hepatology
Manuscript Type Case Control Study
Article Title Circulating microRNA 9-3p and serum endocan as potential biomarkers for hepatitis C virus-related hepatocellular carcinoma
Manuscript Source Invited Manuscript
All Author List Amany Mohamed Salah Eldin Wahb, Mohamed El Kassas, Ahmed Kamal Khamis, Mostafa Elhelbawy, Nesreen Elhelbawy and Mona Salah Eldin Habieb
ORCID
Author(s) ORCID Number
Amany Mohamed Salah Eldin Wahb http://orcid.org/0000-0001-7063-4285
Mohamed El Kassas http://orcid.org/0000-0002-3396-6894
Ahmed Kamal Khamis http://orcid.org/0000-0002-9326-662X
Mostafa Elhelbawy http://orcid.org/0000-0002-6945-6205
Nesreen Elhelbawy http://orcid.org/0000-0002-9231-0342
Mona Salah Eldin Habieb http://orcid.org/0000-0002-4433-0584
Funding Agency and Grant Number
Corresponding Author Mohamed El Kassas, MD, Associate Professor, Department of Endemic Medicine, Faculty of Medicine, Helwan University, Ain Helwan, Cairo 11795, Egypt. m_elkassas@hq.helwan.edu.eg
Key Words microRNA 9-3p; Hepatocellular carcinoma; Endocan; Diagnostic; Biomarker; Egypt
Core Tip Comparing hepatitis C virus (HCV)-related hepatocellular carcinoma (HCC) patients with patients with HCV-induced chronic liver disease and healthy controls reveals that the level of circulating microRNA 9-3p is significantly decreased in HCC patients than in the chronic liver disease and control groups, the level of serum endocan is significantly increased in HCC patients than in the cirrhotic and control groups, better diagnostic performance of microRNA 9-3p and endocan than α-fetoprotein. The levels of microRNA 9-3p have a significant inverse correlation with endocan and vascular invasion and advanced stage of Barcelona Clinical Liver Cancer in the HCC group. So, circulating microRNA 9-3p and endocan could be novel biomarkers for early diagnosis of HCV-related HCC patients.
Publish Date 2021-11-24 09:54
Citation Wahb A, El Kassas M, Khamis AK, Elhelbawy M, Elhelbawy N, Habieb M. Circulating microRNA 9-3p and serum endocan as potential biomarkers for hepatitis C virus-related hepatocellular carcinoma. World J Hepatol 2021; 13(11): 1753-1765
URL https://www.wjgnet.com/1948-5182/full/v13/i11/1753.htm
DOI https://dx.doi.org/10.4254/wjh.v13.i11.1753
Full Article (PDF) WJH-13-1753.pdf
Full Article (Word) WJH-13-1753.docx
Manuscript File 67173-Review-FilipodiaCL.docx
Answering Reviewers 67173-Answering reviewers.pdf
Audio Core Tip 67173-Audio core tip.mp3
Biostatistics Review Certificate 67173-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 67173-Conflict-of-interest statement.pdf
Copyright License Agreement 67173-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s) 67173-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 67173-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 67173-Language certificate.pdf
Peer-review Report 67173-Peer-review(s).pdf
Scientific Misconduct Check 67173-Bing-Wang LL-2.png
Scientific Misconduct Check 67173-Scientific misconduct check.pdf
Scientific Editor Work List 67173-Scientific editor work list.pdf