Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	67359
Country	China

Received	2021-04-22 10:31
Peer-Review Started	2021-04-22 10:33
To Make the First Decision
Return for Revision	2021-06-16 02:02
Revised	2021-06-22 09:15
Second Decision	2021-12-08 07:01
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2021-12-10 03:40
Articles in Press	2021-12-10 03:40
Publication Fee Transferred
Edit the Manuscript by Language Editor	2021-12-06 00:57
Typeset the Manuscript	2021-12-31 06:41
Publish the Manuscript Online	2022-01-11 00:11

ISSN	1948-5204 (online)
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Category	Geriatrics & Gerontology
Manuscript Type	Minireviews
Article Title	Immune evasion mechanisms and therapeutic strategies in gastric cancer
Manuscript Source	Invited Manuscript
All Author List	En-Si Ma, Zheng-Xin Wang, Meng-Qi Zhu and Jing Zhao
ORCID	Author(s) ORCID Number En-Si Ma http://orcid.org/0000-0002-8702-9839 Zheng-Xin Wang http://orcid.org/0000-0002-3354-339X Meng-Qi Zhu http://orcid.org/0000-0002-0092-3900 Jing Zhao http://orcid.org/0000-0003-2446-7732
Funding Agency and Grant Number
Corresponding Author	Jing Zhao, PhD, Associate Professor, Department of General Surgery, Huashan Hospital, Fudan University, No.12 Urumqi Middle Road, Shanghai 200040, China. jingzhao@fudan.edu.cn
Key Words	Gastric cancer; Immune evasion; Immune checkpoint; Immunotherapy; Microenvironment
Core Tip	Gastric cancer (GC) is one of the most common malignancies with high incidence and mortality. GC can exert versatile mechanisms to induce immune evasion. Here, we systematically summarized the intricate crosstalk among GC cells and various immune cells and mainly focused on how GC cells educate immune cells to create an immunosuppressive microenvironment and facilitate GC cells from attack of the immune system. In addition, we retrieved the latest progression of immune checkpoint inhibitor-based immunotherapies and their combination with conventional therapies. This review provides a comprehensive understanding of the immune evasion mechanism and immunotherapeutic strategies in GC.
Publish Date	2022-01-11 00:11
Citation	Ma ES, Wang ZX, Zhu MQ, Zhao J. Immune evasion mechanisms and therapeutic strategies in gastric cancer. World J Gastrointest Oncol 2022; 14(1): 216-229
URL	https://www.wjgnet.com/1948-5204/full/v14/i1/216.htm
DOI	https://dx.doi.org/10.4251/wjgo.v14.i1.216

Full Article (PDF)	WJGO-14-216.pdf
Full Article (Word)	WJGO-14-216.docx
Manuscript File	67359_Auto_Edited-JLW-Filipodia.docx
Answering Reviewers	67359-Answering reviewers.pdf
Audio Core Tip	67359-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	67359-Conflict-of-interest statement.pdf
Copyright License Agreement	67359-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	67359-Grant application form(s).pdf
Non-Native Speakers of English Editing Certificate	67359-Language certificate.pdf
Peer-review Report	67359-Peer-review(s).pdf
Scientific Editor Work List	67359-Scientific editor work list.pdf
CrossCheck Report	67359-CrossCheck report.pdf