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1/11/2022 12:11:23 AM | Browse: 273 | Download: 571
Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 67359
Country/Territory China
2021-04-22 10:31
Peer-Review Started
2021-04-22 10:33
To Make the First Decision
Return for Revision
2021-06-16 02:02
2021-06-22 09:15
Second Decision
2021-12-08 07:01
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2021-12-10 03:40
Articles in Press
2021-12-10 03:40
Publication Fee Transferred
Edit the Manuscript by Language Editor
2021-12-06 00:57
Typeset the Manuscript
2021-12-31 06:41
Publish the Manuscript Online
2022-01-11 00:11
ISSN 1948-5204 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Geriatrics & Gerontology
Manuscript Type Minireviews
Article Title Immune evasion mechanisms and therapeutic strategies in gastric cancer
Manuscript Source Invited Manuscript
All Author List En-Si Ma, Zheng-Xin Wang, Meng-Qi Zhu and Jing Zhao
Author(s) ORCID Number
En-Si Ma http://orcid.org/0000-0002-8702-9839
Zheng-Xin Wang http://orcid.org/0000-0002-3354-339X
Meng-Qi Zhu http://orcid.org/0000-0002-0092-3900
Jing Zhao http://orcid.org/0000-0003-2446-7732
Funding Agency and Grant Number
Corresponding Author Jing Zhao, PhD, Associate Professor, Department of General Surgery, Huashan Hospital, Fudan University, No.12 Urumqi Middle Road, Shanghai 200040, China. jingzhao@fudan.edu.cn
Key Words Gastric cancer; Immune evasion; Immune checkpoint; Immunotherapy; Microenvironment
Core Tip Gastric cancer (GC) is one of the most common malignancies with high incidence and mortality. GC can exert versatile mechanisms to induce immune evasion. Here, we systematically summarized the intricate crosstalk among GC cells and various immune cells and mainly focused on how GC cells educate immune cells to create an immunosuppressive microenvironment and facilitate GC cells from attack of the immune system. In addition, we retrieved the latest progression of immune checkpoint inhibitor-based immunotherapies and their combination with conventional therapies. This review provides a comprehensive understanding of the immune evasion mechanism and immunotherapeutic strategies in GC.
Publish Date 2022-01-11 00:11
Citation Ma ES, Wang ZX, Zhu MQ, Zhao J. Immune evasion mechanisms and therapeutic strategies in gastric cancer. World J Gastrointest Oncol 2022; 14(1): 216-229
URL https://www.wjgnet.com/1948-5204/full/v14/i1/216.htm
DOI https://dx.doi.org/10.4251/wjgo.v14.i1.216
Full Article (PDF) WJGO-14-216.pdf
Full Article (Word) WJGO-14-216.docx
Manuscript File 67359_Auto_Edited-JLW-Filipodia.docx
Answering Reviewers 67359-Answering reviewers.pdf
Audio Core Tip 67359-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 67359-Conflict-of-interest statement.pdf
Copyright License Agreement 67359-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 67359-Grant application form(s).pdf
Non-Native Speakers of English Editing Certificate 67359-Language certificate.pdf
Peer-review Report 67359-Peer-review(s).pdf
Scientific Editor Work List 67359-Scientific editor work list.pdf