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10/13/2021 12:57:54 PM | Browse: 22 | Download: 46
Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 67530
Country/Territory Argentina
Received
2021-04-27 13:09
Peer-Review Started
2021-04-27 13:12
To Make the First Decision
Return for Revision
2021-06-15 15:37
Revised
2021-06-28 16:13
Second Decision
2021-08-27 03:15
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2021-08-27 11:04
Articles in Press
2021-08-27 11:04
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2021-10-08 12:10
Publish the Manuscript Online
2021-10-13 12:57
ISSN 1948-5204 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Biochemistry and Molecular Biology
Manuscript Type Basic Study
Article Title Survival effect of probiotics in a rat model of colorectal cancer treated with capecitabine
Manuscript Source Invited Manuscript
All Author List Graciela Gigola, Pedro Carriere, María Belén Novoa Díaz, Gabriela Perdigon, Ariel Osvaldo Zwenger and Claudia Gentili
ORCID
Author(s) ORCID Number
Graciela Gigola http://orcid.org/0000-0001-7362-3178
Pedro Carriere http://orcid.org/0000-0002-5751-8850
María Belén Novoa Díaz http://orcid.org/0000-0002-6684-4076
Gabriela Perdigon http://orcid.org/0000-0001-9856-0812
Ariel Osvaldo Zwenger http://orcid.org/0000-0002-4407-5413
Claudia Gentili http://orcid.org/0000-0002-9957-7824
Funding Agency and Grant Number
Funding Agency Grant Number
Universidad Nacional del Sur, Argentina GI 24/B138
Universidad Nacional del Sur, Argentina PGI 24/ZB50
Universidad Nacional del Sur, Argentina PGI 24/ZB63
Corresponding Author Graciela Gigola, PhD, Doctor, Professor, Biología, Bioquímica y Farmacia, Universidad Nacional del Sur (UNS)- INBIOSUR (CONICET-UNS), San Juan 670, Bahía Blanca 8000, Buenos Aires Provincia, Argentina. ggigola@uns.edu.ar
Key Words Colorectal cancer; Capecitabine; Probiotics; Survival; Life quality; Animal experimentation
Core Tip Today it is still unclear which are the most effective forms of probiotics administration at long-term to reduce the incidence of human colorectal cancer (CRC) or which microorganisms are the most suitable; the amount, time and frequency that should be consumed in the diet. Also, which is their influence on side effect from chemotherapy in CRC? Herein we show, for the first time, that probiotics have a positive impact on the overall survival of rats with CRC under capecitabine treatment. These animals have also a benefit in weight gain, clinical manifestations, developing cancer, number, localization and tumor burden.
Publish Date 2021-10-13 12:57
Citation Gigola G, Carriere P, Novoa Díaz MB, Perdigon G, Zwenger AO, Gentili C. Survival effect of probiotics in a rat model of colorectal cancer treated with capecitabine. World J Gastrointest Oncol 2021; 13(10): 1518-1531
URL https://www.wjgnet.com/1948-5204/full/v13/i10/1518.htm
DOI https://dx.doi.org/10.4251/wjgo.v13.i10.1518
Full Article (PDF) WJGO-13-1518.pdf
Full Article (Word) WJGO-13-1518.docx
Manuscript File 67530_Auto_Edited-JLW.docx
Answering Reviewers 67530-Answering reviewers.pdf
Audio Core Tip 67530-Audio core tip.mpeg
Biostatistics Review Certificate 67530-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 67530-Conflict-of-interest statement.pdf
Copyright License Agreement 67530-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 67530-Grant application form(s).pdf
Institutional Animal Care and Use Committee Approval Form or Document 67530-Institutional animal care and use committee statement.pdf
Institutional Review Board Approval Form or Document 67530-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 67530-Language certificate.pdf
Peer-review Report 67530-Peer-review(s).pdf
Scientific Misconduct Check 67530-Scientific misconduct check.pdf
Scientific Editor Work List 67530-Scientific editor work list.pdf