Publication Name	World Journal of Stem Cells
Manuscript ID	67752
Country	China

Received	2021-05-05 09:18
Peer-Review Started	2021-05-05 09:21
To Make the First Decision
Return for Revision	2021-06-23 14:53
Revised	2021-07-20 12:10
Second Decision	2021-12-24 04:48
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2021-12-25 20:00
Articles in Press	2021-12-25 20:00
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2022-01-06 08:33
Publish the Manuscript Online	2022-01-20 10:47

ISSN	1948-0210 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Cell Biology
Manuscript Type	Basic Study
Article Title	Therapeutic effects of menstrual blood-derived endometrial stem cells on mouse models of streptozotocin-induced type 1 diabetes
Manuscript Source	Invited Manuscript
All Author List	Yu-Liang Sun, Ling-Rui Shang, Rui-Hong Liu, Xin-Yi Li, Sheng-Hui Zhang, Ya-Kun Ren, Kang Fu, Hong-Bin Cheng, Badrul Hisham Yahaya, Yan-Li Liu and Jun-Tang Lin
ORCID	Author(s) ORCID Number Yu-Liang Sun http://orcid.org/0000-0002-6338-0077 Ling-Rui Shang http://orcid.org/0000-0001-5007-0646 Rui-Hong Liu http://orcid.org/0000-0003-2449-161X Xin-Yi Li http://orcid.org/0000-0001-7578-3183 Sheng-Hui Zhang http://orcid.org/0000-0002-2760-6550 Ya-Kun Ren http://orcid.org/0000-0002-7961-8430 Kang Fu http://orcid.org/0000-0002-9228-3161 Hong-Bin Cheng http://orcid.org/0000-0001-8963-8702 Badrul Hisham Yahaya http://orcid.org/0000-0002-3295-9676 Yan-Li Liu http://orcid.org/0000-0003-0886-8907 Jun-Tang Lin http://orcid.org/0000-0001-9300-1771
Funding Agency and Grant Number	Funding Agency Grant Number Henan Province Foundation of China 202300410307 Henan Province Foundation of China 212102310611 Xinxiang City Foundation of China GG2020009
Corresponding Author	Jun-Tang Lin, PhD, Professor, Stem Cell and Biotherapy Technology Research Center, Xinxiang Medical University, East of JinSui Road, Xinxiang 453000, Henan Province, China. linjt@xxmu.edu.cn
Key Words	Type 1 diabetes; Menstrual blood-derived endometrial stem cell; Umbilical cord mesenchymal stem cells; Improvement; Complication
Core Tip	Mesenchymal stem cell (MSC)-based therapies have resulted in promising improvements for patients with type 1 diabetes (T1D). Menstrual blood-derived endometrial stem cells (MenSC) transplantation has therapeutic effects equal to those of umbilical cord-derived MSC, which can significantly improve the symptoms of streptozotocin-induced T1D mice and exert protective effects on their main organs; MSC-induced angiogenesis, antiapoptotic effects and immunomodulation contribute to these protective effects. The results of this study showed that MenSC are expected to become a promising alternative for clinical diabetes treatment due to their advantages, including their regular and noninvasive collection protocol, abundant availability, and superior proliferative capacity.
Publish Date	2022-01-20 10:47
Citation	Sun YL, Shang LR, Liu RH, Li XY, Zhang SH, Ren YK, Fu K, Cheng HB, Yahaya BH, Liu YL, Lin JT. Therapeutic effects of menstrual blood-derived endometrial stem cells on mouse models of streptozotocin-induced type 1 diabetes. World J Stem Cells 2022; 14(1): 104-116
URL	https://www.wjgnet.com/1948-0210/full/v14/i1/104.htm
DOI	https://dx.doi.org/10.4252/wjsc.v14.i1.104

Full Article (PDF)	WJSC-14-104.pdf
Full Article (Word)	WJSC-14-104.docx
Manuscript File	67752_Auto_Edited.docx
Answering Reviewers	67752-Answering reviewers.pdf
Audio Core Tip	67752-Audio core tip.m4a
Biostatistics Review Certificate	67752-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	67752-Conflict-of-interest statement.pdf
Copyright License Agreement	67752-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	67752-Grant application form(s).pdf
Institutional Animal Care and Use Committee Approval Form or Document	67752-Institutional animal care and use committee statement.pdf
Non-Native Speakers of English Editing Certificate	67752-Language certificate.pdf
Peer-review Report	67752-Peer-review(s).pdf
Scientific Misconduct Check	67752-Bing-Fan JR-2.png
Scientific Editor Work List	67752-Scientific editor work list.pdf