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Articles Published Processes
9/10/2014 7:22:00 PM | Browse: 1050 | Download: 967
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Received |
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2013-10-29 09:46 |
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Peer-Review Started |
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2013-10-30 10:44 |
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To Make the First Decision |
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2013-12-25 18:00 |
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Return for Revision |
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2013-12-30 15:49 |
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Revised |
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2014-01-09 13:29 |
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Second Decision |
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2014-03-04 09:59 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2014-03-04 10:30 |
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Articles in Press |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2014-05-08 20:34 |
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Publish the Manuscript Online |
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2014-05-20 15:05 |
Category |
Pathology |
Manuscript Type |
Review |
Article Title |
Mechanisms of fibrogenesis in liver cirrhosis: The molecular aspects of epithelial-mesenchymal transition
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Manuscript Source |
Invited Manuscript |
All Author List |
Sun-Jae Lee, Kyung-Hyun Kim and Kwan-Kyu Park |
Funding Agency and Grant Number |
Funding Agency |
Grant Number |
National Research Foundation of Korea |
2012R1A1A401015639 |
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Corresponding Author |
Kwan-Kyu Park, MD, PhD, Department of Pathology, Catholic University of Daegu, College of Medicine, 3056-6 Daemyung 4-Dong, Nam-Gu, Daegu, 705-718, South Korea. kkpark@cu.ac.kr |
Key Words |
Epithelial-mesenchymal transition; Liver; Fibrosis; Transforming growth factor-beta1; Biological markers |
Core Tip |
The cause of fibrosis and diminished regeneration, especially in liver cirrhosis, is still unknown. Epithelial-mesenchymal transition (EMT) has been found to be associated with liver fibrosis. The possibility that EMT could contribute to hepatic fibrogenesis reinforced the concept that activated hepatic stellate cells are not the only key players in the hepatic fibrogenic process. The aim of this article is to describe how EMT participates to hepatic fibrosis and discuss the evidence of supporting this possibility in order to reach reasonable and useful conclusions. |
Publish Date |
2014-05-20 15:05 |
Citation |
Lee SJ, Kim KH, Park KK. Mechanisms of fibrogenesis in liver cirrhosis: The molecular aspects of epithelial-mesenchymal transition. World J Hepatol 2014; 6(4): 207-216 |
URL |
http://www.wjgnet.com/1948-5182/full/v6/i4/207.htm |
DOI |
http://dx.doi.org/10.4254/wjh.v6.i4.207 |
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