BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
11/19/2021 11:15:33 AM | Browse: 443 | Download: 1045
 |
Received |
|
2021-05-19 15:32 |
|
Peer-Review Started |
|
2021-05-19 15:34 |
 |
To Make the First Decision |
|
|
|
Return for Revision |
|
2021-06-22 19:21 |
|
Revised |
|
2021-07-05 15:11 |
|
Second Decision |
|
2021-09-13 02:26 |
|
Accepted by Journal Editor-in-Chief |
|
|
|
Accepted by Executive Editor-in-Chief |
|
2021-09-16 23:48 |
|
Articles in Press |
|
2021-09-16 23:48 |
|
Publication Fee Transferred |
|
|
|
Edit the Manuscript by Language Editor |
|
2021-10-22 05:49 |
|
Typeset the Manuscript |
|
2021-11-16 10:26 |
|
Publish the Manuscript Online |
|
2021-11-19 11:15 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Basic Study |
| Article Title |
Genome-wide map of N6-methyladenosine circular RNAs identified in mice model of severe acute pancreatitis
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Jun Wu, Xiao-Hui Yuan, Wen Jiang, Yi-Chen Lu, Qi-Lin Huang, Yi Yang, Hua-Ji Qie, Jiang-Tao Liu, Hong-Yu Sun and Li-Jun Tang |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
81772001 |
| National Clinical Key Subject of China |
41792113 |
|
| Corresponding Author |
Li-Jun Tang, MD, PhD, Chief Doctor, Professor, Department of General Surgery and Pancreatic Injury and Repair Key Laboratory of Sichuan Province, The General Hospital of Western Theater Command, No. 270 Tianhuan Road, Furong Avenue, Jinniu District, Chengdu 610036, Sichuan Province, China. tanglj2016@163.com |
| Key Words |
Severe acute pancreatitis; Circular RNAs; N6-methyladenosine; MeRIP-seq; Epigenetic analysis |
| Core Tip |
We identified transcriptome-wide map of N6-methyladenosine (m6A) circRNAs and determined their biological significance and potential mechanisms in severe acute pancreatitis (SAP). The main findings were: (1) Function analysis found that circRNAs with differentially expressed m6A peaks were involved in the key process of SAP; (2) m6A may affect the interplays of circRNAs and microRNAs to participate in the pathogenesis of SAP; and (3) Demethylase alkylation repair homolog 5 may play key roles in dynamic process of m6A to downregulate the total m6A level of circRNAs in SAP. We provided novel insights to explore the possible pathophysiological mechanism of SAP and seek new potential therapeutic targets. |
| Publish Date |
2021-11-19 11:15 |
| Citation |
Wu J, Yuan XH, Jiang W, Lu YC, Huang QL, Yang Y, Qie HJ, Liu JT, Sun HY, Tang LJ. Genome-wide map of N6-methyladenosine circular RNAs identified in mice model of severe acute pancreatitis. World J Gastroenterol 2021; 27(43): 7530-7545 |
| URL |
https://www.wjgnet.com/1007-9327/full/v27/i43/7530.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v27.i43.7530 |
© 2004-2025 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
California Corporate Number: 3537345
