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1/11/2022 12:11:23 AM | Browse: 320 | Download: 669
Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 71395
Country China
Received
2021-09-06 13:23
Peer-Review Started
2021-09-06 13:25
To Make the First Decision
Return for Revision
2021-11-08 12:40
Revised
2021-11-18 17:55
Second Decision
2021-12-07 03:16
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2021-12-08 06:00
Articles in Press
2021-12-08 06:00
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2021-12-31 04:31
Publish the Manuscript Online
2022-01-11 00:11
ISSN 1948-5204 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Retrospective Study
Article Title Characterization of E-cadherin expression in normal mucosa, dysplasia and adenocarcinoma of gastric cardia and its influence on prognosis
Manuscript Source Unsolicited Manuscript
All Author List Hai-Ling Wang, Xue-Ke Zhao, Fu-You Zhou, Xin Song, Liu-Yu Li, Gai-Rong Huang, Qi-De Bao, Ling-Ling Lei, Hai-Jun Yang, Li Li, Rui-Hua Xu, Ai-Li Li, Xian-Zeng Wang, Wen-Li Han, Jing-Li Ren and Li-Dong Wang
ORCID
Author(s) ORCID Number
Hai-Ling Wang http://orcid.org/0000-0003-4437-2052
Xue-Ke Zhao http://orcid.org/0000-0002-9036-6342
Fu-You Zhou http://orcid.org/0000-0002-6548-4099
Xin Song http://orcid.org/0000-0002-7680-4908
Liu-Yu Li http://orcid.org/0000-0001-6748-3295
Gai-Rong Huang http://orcid.org/0000-0002-7034-0444
Qi-De Bao http://orcid.org/0000-0002-5746-0273
Ling-Ling Lei http://orcid.org/0000-0001-7540-7786
Hai-Jun Yang http://orcid.org/0000-0002-8663-7779
Li Li http://orcid.org/0000-0001-9567-5403
Rui-Hua Xu http://orcid.org/0000-0002-6914-2168
Ai-Li Li http://orcid.org/0000-0002-1143-7393
Xian-Zeng Wang http://orcid.org/0000-0001-5691-8898
Wen-Li Han http://orcid.org/0000-0002-3516-2195
Jing-Li Ren http://orcid.org/0000-0001-9891-0579
Li-Dong Wang http://orcid.org/0000-0002-7933-0410
Funding Agency and Grant Number
Funding Agency Grant Number
National Natural Science Foundation of China 81872032
National Natural Science Foundation of China U1804262
National Key R&D Program of China 2016YFC0901403
Corresponding Author Li-Dong Wang, MD, PhD, Professor, State Key Laboratory of Esophageal Cancer Prevention & Treatment and Henan Key Laboratory for Esophageal Cancer Research, The First Affiliated Hospital of Zhengzhou University, No. 40 Daxue Road, Zhengzhou 450052, Henan Province, China. ldwang2007@126.com
Key Words E-cadherin expression; Immunohistochemistry; Gastric cardia adenocarcinoma; Dysplasia; Clinicopathological feature; Prognosis
Core Tip In previous reports, there is no consistent conclusion on the association between E-cadherin expression and gastric cardia carcinogenesis and its effect on prognosis with gastric cardia adenocarcinoma (GCA) patients. It was notable that the positive immunostaining rates of E-cadherin decreased significantly from normal mucosa to dysplasia and GCA, as well as higher in early stage than those in advanced stage of GCA. Moreover, we found high expression of E–cadherin represented a better survival, especially for patients with negative lymph node metastasis. In conclusion, E-cadherin may be involved in carcinogenesis and may be a predictor on prognosis for GCA.
Publish Date 2022-01-11 00:11
Citation Wang HL, Zhao XK, Zhou FY, Song X, Li LY, Huang GR, Bao QD, Lei LL, Yang HJ, Li L, Xu RH, Li AL, Wang XZ, Han WL, Ren JL, Wang LD. Characterization of E-cadherin expression in normal mucosa, dysplasia and adenocarcinoma of gastric cardia and its influence on prognosis. World J Gastrointest Oncol 2022; 14(1): 265-277
URL https://www.wjgnet.com/1948-5204/full/v14/i1/265.htm
DOI https://dx.doi.org/10.4251/wjgo.v14.i1.265
Full Article (PDF) WJGO-14-265.pdf
Full Article (Word) WJGO-14-265.docx
Manuscript File 71395_Auto_Edited.docx
Answering Reviewers 71395-Answering reviewers.pdf
Audio Core Tip 71395-Audio core tip.m4a
Biostatistics Review Certificate 71395-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 71395-Conflict-of-interest statement.pdf
Copyright License Agreement 71395-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 71395-Grant application form(s).pdf
Institutional Review Board Approval Form or Document 71395-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 71395-Language certificate.pdf
Supplementary Material 71395-Supplementary material.pdf
Peer-review Report 71395-Peer-review(s).pdf
Scientific Misconduct Check 71395-Bing-Fan JR-2.png
Scientific Editor Work List 71395-Scientific editor work list.pdf
CrossCheck Report 71395-CrossCheck report.pdf
CrossCheck Report 71395-CrossCheck.png