Publication Name	World Journal of Diabetes
Manuscript ID	72416
Country	China

Received	2021-10-15 08:13
Peer-Review Started	2021-10-15 08:15
To Make the First Decision
Return for Revision	2021-12-27 07:16
Revised	2022-01-24 08:09
Second Decision	2022-03-10 05:48
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2022-03-17 04:57
Articles in Press	2022-03-17 04:57
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2022-04-07 06:22
Publish the Manuscript Online	2022-04-14 11:27

ISSN	1948-9358 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright	©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Urology & Nephrology
Manuscript Type	Basic Study
Article Title	Long noncoding RNA X-inactive specific transcript regulates NLR family pyrin domain containing 3/caspase-1-mediated pyroptosis in diabetic nephropathy
Manuscript Source	Unsolicited Manuscript
All Author List	Jia Xu, Qin Wang, Yi-Fan Song, Xiao-Hui Xu, He Zhu, Pei-Dan Chen and Ye-Ping Ren
ORCID	Author(s) ORCID Number Jia Xu http://orcid.org/0000-0004-2463-5123 Qin Wang http://orcid.org/0000-0002-6135-4135 Yi-Fan Song http://orcid.org/0000-0003-4163-4135 Xiao-Hui Xu http://orcid.org/0000-0002-4153-2416 He Zhu http://orcid.org/0000-0004-2413-6223 Pei-Dan Chen http://orcid.org/0000-0003-4136-5136 Ye-Ping Ren http://orcid.org/0000-0002-4740-2803
Funding Agency and Grant Number	Funding Agency Grant Number Natural Science Foundation of Shenzhen University General Hospital SUGH2020QD011
Corresponding Author	Ye-Ping Ren, PhD, Chief Doctor, Nephrology, Shenzhen University General Hospital, No.1098 Xueyuan Road, Nanshan District, Shenzhen 518000, Guangdong Province, China. drrenyeping123@163.com
Key Words	Diabetic nephropathy; Pyroptosis; Renal tubular epithelial cell; Long noncoding RNA X-inactive specific transcript; microRNA-15b-5p; Toll-like receptor 4; NLR family pyrin domain containing 3/caspase-1 pathway
Core Tip	We investigated the mechanism of long noncoding RNA X-inactive specific transcript (XIST) on NLR family pyrin domain containing 3/caspase-1-mediated renal tubular epithelial pyroptosis through the microRNA-15-5p/Toll-like receptor 4 axis and identified XIST as a possible molecular target to mediate renal tubular epithelial pyroptosis in the treatment of renal injury in diabetic nephropathy.
Publish Date	2022-04-14 11:27
Citation	Xu J, Wang Q, Song YF, Xu XH, Zhu H, Chen PD, Ren YP. Long noncoding RNA X-inactive specific transcript regulates NLR family pyrin domain containing 3/caspase-1-mediated pyroptosis in diabetic nephropathy. World J Diabetes 2022; 13(4): 358-375
URL	https://www.wjgnet.com/1948-9358/full/v13/i4/358.htm
DOI	https://dx.doi.org/10.4239/wjd.v13.i4.358

Full Article (PDF)	WJD-13-358.pdf
Full Article (Word)	WJD-13-358.docx
The ARRIVE Guidelines	72416-The-ARRIVE-Guidelines-revision.pdf
Manuscript File	72416_Auto_Edited.docx
Answering Reviewers	72416-Answering reviewers.pdf
Audio Core Tip	72416-Audio core tip.m4a
Biostatistics Review Certificate	72416-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	72416-Conflict-of-interest statement.pdf
Copyright License Agreement	72416-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	72416-Grant application form(s).pdf
Institutional Animal Care and Use Committee Approval Form or Document	72416-Institutional animal care and use committee statement.pdf
Non-Native Speakers of English Editing Certificate	72416-Language certificate.pdf
Peer-review Report	72416-Peer-review(s).pdf
Scientific Misconduct Check	72416-Bing-Wu YXJ-2.png
Scientific Misconduct Check	72416-Scientific editor work list.pdf