ISSN |
1007-9327 (print) and 2219-2840 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Surgery |
Manuscript Type |
Retrospective Cohort Study |
Article Title |
Incidental gallbladder cancer diagnosis confers survival advantage irrespective of tumour stage and characteristics
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Manuscript Source |
Unsolicited Manuscript |
All Author List |
Moath Alarabiyat, Syed Soulat Raza, John Isaac, Darius Mirza, Ravi Marudanayagam, Keith Roberts, Manuel Abradelo, David C Bartlett, Bobby V Dasari, Robert P Sutcliffe and Nikolaos A Chatzizacharias |
ORCID |
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Funding Agency and Grant Number |
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Corresponding Author |
Nikolaos A Chatzizacharias, FACS, FRCS, MD, PhD, Surgeon, Department of HPB and liver transplantation, Queen Elizabeth Hospital, University Hospitals Birmingham, 3rd Floor, Nuffield House, Mindelsohn way, Birmingham B15 2TH, United Kingdom. chatzizacharias@gmail.com |
Key Words |
Gallbladder cancer; Incidental gallbladder cancer; Non-incidental gallbladder cancer; Gallbladder cancer survival |
Core Tip |
Data are conflicting on the role of incidental gallbladder cancer (IGBC) diagnosis in oncological outcomes. Some studies suggest that IGBC diagnosis does not affect outcomes, while others that overall survival (OS) is longer in these cases compared to non-incidental diagnosis (NIGBC). In our study, IGBC diagnosis conferred better OS in all patients with gallbladder cancer, as well as within the surgical and non-surgical groups. Similarly, disease free survival was significantly longer in patients with IGBC. NIGBC diagnosis was identified as an independent predictor of OS along with N stage and resection margin status. |
Publish Date |
2022-05-12 08:42 |
Citation |
Alarabiyat M, Raza SS, Isaac J, Mirza D, Marudanayagam R, Roberts K, Abradelo M, Bartlett DC, Dasari BV, Sutcliffe RP, Chatzizacharias NA. Incidental gallbladder cancer diagnosis confers survival advantage irrespective of tumour stage and characteristics. World J Gastroenterol 2022; 28(18): 1996-2007 |
URL |
https://www.wjgnet.com/1007-9327/full/v28/i18/1996.htm |
DOI |
https://dx.doi.org/10.3748/wjg.v28.i18.1996 |