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5/24/2022 10:35:19 AM | Browse: 265 | Download: 529
Publication Name World Journal of Hepatology
Manuscript ID 73679
Country/Territory Italy
Received
2021-11-30 11:09
Peer-Review Started
2021-11-30 11:11
To Make the First Decision
Return for Revision
2021-12-27 20:33
Revised
2022-01-31 07:08
Second Decision
2022-04-21 02:23
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2022-04-25 20:07
Articles in Press
2022-04-25 20:07
Publication Fee Transferred
Edit the Manuscript by Language Editor
2022-04-05 14:16
Typeset the Manuscript
2022-05-07 02:08
Publish the Manuscript Online
2022-05-24 10:35
ISSN 1948-5182 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Review
Article Title Role of hepatitis B virus in development of hepatocellular carcinoma: Focus on covalently closed circular DNA
Manuscript Source Invited Manuscript
All Author List Claryssa Bianca, Elizabeth Sidhartha, Claudio Tiribelli, Korri Elvanita El-Khobar and Caecilia H C Sukowati
ORCID
Author(s) ORCID Number
Claryssa Bianca http://orcid.org/0000-0001-8208-8824
Elizabeth Sidhartha http://orcid.org/0000-0002-1475-4693
Claudio Tiribelli http://orcid.org/0000-0001-6596-7595
Korri Elvanita El-Khobar http://orcid.org/0000-0002-9383-931X
Caecilia H C Sukowati http://orcid.org/0000-0001-9699-7578
Funding Agency and Grant Number
Funding Agency Grant Number
Regione of Friuli Venezia Giulia, Italy DGR 189 dd 12/2/21 to the FIF
Corresponding Author Caecilia H C Sukowati, BSc, PhD, Senior Researcher, Centro Studi Fegato, Fondazione Italiana Fegato ONLUS, AREA Science Park, campus Basovizza, SS14 km 163.5, Trieste 34149, Italy. caecilia.sukowati@fegato.it
Key Words Hepatitis B virus; Covalently closed circular DNA; Hepatocellular carcinoma; Hepatocarcinogenesis
Core Tip The covalently closed circular DNA (cccDNA) of hepatitis B virus (HBV) in human hepatocytes serves as the template for viral replication machinery. HBV cccDNA is also related to host immune response and persistent HBV infection leading to the development of hepatocellular carcinoma. This review summarizes current knowledge on cccDNA in hepatocarcinogenesis and comprehensive efforts to its detection and targeting.
Publish Date 2022-05-24 10:35
Citation Bianca C, Sidhartha E, Tiribelli C, El-Khobar KE, Sukowati CHC. Role of hepatitis B virus in development of hepatocellular carcinoma: Focus on covalently closed circular DNA. World J Hepatol 2022;14(5): 866-884
URL https://www.wjgnet.com/1948-5182/full/v14/i5/866.htm
DOI https://dx.doi.org/10.4254/wjh.v14.i5.866
Full Article (PDF) WJH-14-866.pdf
Full Article (Word) WJH-14-866.docx
Manuscript File 73679_Auto_Edited_LM.docx
Answering Reviewers 73679-Answering reviewers.pdf
Audio Core Tip 73679-Audio core tip.m4a
Conflict-of-Interest Disclosure Form 73679-Conflict-of-interest statement.pdf
Copyright License Agreement 73679-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 73679-Grant application form(s).pdf
Non-Native Speakers of English Editing Certificate 73679-Language certificate.pdf
Peer-review Report 73679-Peer-review(s).pdf
Scientific Misconduct Check 73679-Bing-Liu JH-2.jpg
Scientific Misconduct Check 73679-CrossCheck.jpg
Scientific Editor Work List 73679-Scientific editor work list.pdf