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Articles Published Processes
8/3/2022 7:54:39 AM | Browse: 196 | Download: 328
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Received |
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2021-12-03 16:04 |
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Peer-Review Started |
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2021-12-03 16:05 |
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To Make the First Decision |
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Return for Revision |
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2022-05-29 08:03 |
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Revised |
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2022-06-06 16:21 |
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Second Decision |
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2022-07-06 08:12 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2022-07-11 18:32 |
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Articles in Press |
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2022-07-11 18:32 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2022-06-28 02:25 |
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Typeset the Manuscript |
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2022-07-25 02:47 |
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Publish the Manuscript Online |
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2022-08-03 07:54 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Minireviews |
| Article Title |
Clinical challenge for gastroenterologists–Gastrointestinal manifestations of systemic mastocytosis: A comprehensive review
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Alessandra Elvevi, Elena Maria Elli, Martina Lucà, Miki Scaravaglio, Fabio Pagni, Stefano Ceola, Laura Ratti, Pietro Invernizzi and Sara Massironi |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Sara Massironi, MD, PhD, Doctor, Gastroenterology Division, San Gerardo Hospital, University of Milano – Bicocca School of Medicine, Via G.B. Pergolesi 33 , Monza 20900, Italy. sara.massironi@libero.it |
| Key Words |
Systemic mastocytosis; Gastrointestinal involvement; Gastrointestinal symptoms |
| Core Tip |
Gastrointestinal (GI) involvement is frequent in systemic disease (SM); GI symptoms are frequent (second in frequency only to itching), being the main culprits of chronic disorders, and are a major determinant of quality of life. GI symptoms could be secondary both to mast cell (MC) mediator release and MC infiltration in the GI tract, causing organ dysfunction. Diagnosis of GI involvement in SM is based on clinical and endoscopic suspicion and histologic demonstration of MC infiltration in GI mucosa, using immunohistochemistry (i.e., CD117, tryptase, CD25). Symptomatic treatment is used to control mediators-release symptoms while cytoreductive therapies are necessary to reduce organ dysfunction secondary to MC infiltration and proliferation. |
| Publish Date |
2022-08-03 07:54 |
| Citation |
Elvevi A, Elli EM, Lucà M, Scaravaglio M, Pagni F, Ceola S, Ratti L, Invernizzi P, Massironi S. Clinical challenge for gastroenterologists–Gastrointestinal manifestations of systemic mastocytosis: A comprehensive review. World J Gastroenterol 2022; 28(29): 3767-3779 |
| URL |
https://www.wjgnet.com/1007-9327/full/v28/i29/3767.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v28.i29.3767 |
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