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6/15/2022 8:13:52 AM | Browse: 68 | Download: 144
Publication Name World Journal of Transplantation
Manuscript ID 74772
Country/Territory Australia
Received
2022-01-10 03:14
Peer-Review Started
2022-01-10 03:15
To Make the First Decision
Return for Revision
2022-04-13 00:42
Revised
2022-04-24 04:43
Second Decision
2022-05-19 03:10
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2022-05-23 00:53
Articles in Press
2022-05-23 00:53
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2022-05-26 09:12
Publish the Manuscript Online
2022-06-15 08:13
ISSN 2220-3230 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology and Hepatology
Manuscript Type Retrospective Study
Article Title Reduced upper limb lean mass on dual energy X-ray absorptiometry predicts adverse outcomes in male liver transplant recipients
Manuscript Source Invited Manuscript
All Author List Penelope Hey, Rudolf Hoermann, Paul Gow, Timothy P Hanrahan, Adam G Testro, Ross Apostolov and Marie Sinclair
ORCID
Author(s) ORCID Number
Penelope Hey http://orcid.org/0000-0002-5219-0382
Rudolf Hoermann http://orcid.org/0000-0002-1326-4270
Paul Gow http://orcid.org/0000-0001-6505-7233
Timothy P Hanrahan http://orcid.org/0000-0003-0657-3048
Adam G Testro http://orcid.org/0000-0001-6776-3115
Ross Apostolov http://orcid.org/0000-0002-4827-8795
Marie Sinclair http://orcid.org/0000-0003-0657-3115
Funding Agency and Grant Number
Corresponding Author Penelope Hey, FRACP, MBBS, Research Fellow, Staff Physician, Liver Transplant Unit, Austin Health, 145 Studley Road, Heidelberg 3084, Australia. penny.hey@austin.org.au
Key Words Dual-energy X-ray absorptiometry; Sarcopenia; Body composition; Liver transplantation; Survival
Core Tip Pre-transplant sarcopenia as measured by single-slice computed tomography has prognostic value in predicting outcomes in liver transplant recipients. In this retrospective study, we explore the association of pre-transplant dual-energy X-ray absorptiometry (DEXA) body composition analysis with early post-transplant outcomes. Low upper limb lean mass (LM) was a predictor of 180-d post-transplant bacterial infections and longer hospital and intensive care length of stay in men but not women. Upper limb LM was superior to other measures of LM including appendicular LM in predicting adverse outcomes. There was no association between pre-transplant body composition and post-transplant mortality, graft failure or early acute cellular rejection. In conclusion, pre-transplant sarcopenia is associated with adverse outcomes in men after liver transplantation. Upper limb LM provides a novel measure of muscle mass that is superior to other measures of LM on DEXA in predicting early post-transplant outcomes.
Publish Date 2022-06-15 08:13
Citation Hey P, Hoermann R, Gow P, Hanrahan TP, Testro AG, Apostolov R, Sinclair M. Reduced upper limb lean mass on dual energy X-ray absorptiometry predicts adverse outcomes in male liver transplant recipients. World J Transplant 2022; 12(6): 120-130
URL https://www.wjgnet.com/2220-3230/full/v12/i6/120.htm
DOI https://dx.doi.org/10.5500/wjt.v12.i6.120
Full Article (PDF) WJT-12-120.pdf
Full Article (Word) WJT-12-120.docx
Manuscript File 74772_Auto_Edited-LS.docx
Answering Reviewers 74772-Answering reviewers.pdf
Audio Core Tip 74772-Audio core tip.m4a
Biostatistics Review Certificate 74772-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 74772-Conflict-of-interest statement.pdf
Copyright License Agreement 74772-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s) 74772-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 74772-Institutional review board statement.pdf
Peer-review Report 74772-Peer-review(s).pdf
Scientific Misconduct Check 74772-Bing-Wang JJ-2.png
Scientific Editor Work List 74772-Scientific editor work list.pdf