Publication Name	World Journal of Gastroenterology
Manuscript ID	7501
Country	India

Received	2013-11-22 08:21
Peer-Review Started	2013-11-22 20:28
To Make the First Decision	2013-12-26 10:59
Return for Revision	2014-03-29 15:35
Revised	2014-02-10 15:55
Second Decision	2014-06-26 17:01
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2014-06-26 17:26
Articles in Press	2014-06-26 17:52
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-09-18 15:29
Publish the Manuscript Online	2014-10-01 20:25

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Microbiology
Manuscript Type	Topic Highlights
Article Title	Diagnosis of Helicobacter pylori: What should be the gold standard?
Manuscript Source	Invited Manuscript
All Author List	Saurabh Kumar Patel, Chandra Bhan Pratap, Ashok Kumar Jain, Anil Kumar Gulati and Gopal Nath
Funding Agency and Grant Number	Funding Agency Grant Number Council of Scientific and Industrial Research, New Delhi, India to Patel SK
Corresponding Author	Gopal Nath, MD, PhD, Department of Microbiology, Institute of Medical Sciences, Banaras Hindu University, Pandit Madan Mohan Malviya Rd, Varanasi, UP 221005, India. gopalnath@gmail.com
Key Words	Helicobacter pylori review; Invasive tests; Non-invasive tests; Gold standard; Polymerase chain reaction detection; Nested polymerase chain reaction
Core Tip	Several detection methods for Helicobacter pylori (H. pylori) have been developed. Noninvasive tests such as serology, 13C Urea breath test and stool antigen tests are usually preferred. Invasive test involving histology, culture, rapid urease test and polymerase chain reaction (PCR) are also available. Each one of them has been associated with one or more advantages or disadvantages. However, PCR is the best method to detect H. pylori in gastric mucosa, gastric juice, saliva, dental plaques and environmental specimens. PCR based diagnosis may be considered as gold standard provided that H. pylori specific primers targeting at least more than one conserved genes are used.
Publish Date	2014-10-01 20:25
Citation	Patel SK, Pratap CB, Jain AK, Gulati AK, Nath G. Diagnosis of Helicobacter pylori: What should be the gold standard? World J Gastroenterol 2014; 20(36): 12847-12859
URL	http://www.wjgnet.com/1007-9327/full/v20/i36/12847.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i36.12847

Full Article (PDF)	WJG-20-12847.pdf
Full Article (Word)	WJG-20-12847.doc
Manuscript File	7501-Review.docx
Answering Reviewers	7501-Answering reviewers.pdf
Copyright License Agreement	7501-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	7501-Language certificate.pdf
Peer-review Report	7501-Peer review.pdf
Scientific Misconduct Check	7501-CorssCheck.jpg
Scientific Editor Work List	7501-Scientific editor work list.pdf