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7/11/2022 5:53:38 AM | Browse: 286 | Download: 510
Publication Name World Journal of Diabetes
Manuscript ID 75512
Country Spain
Received
2022-02-01 15:10
Peer-Review Started
2022-02-01 15:12
To Make the First Decision
Return for Revision
2022-04-18 00:04
Revised
2022-04-19 16:00
Second Decision
2022-06-21 03:08
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2022-06-26 23:48
Articles in Press
2022-06-26 23:48
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2022-07-05 14:21
Publish the Manuscript Online
2022-07-11 05:53
ISSN 1948-9358 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Medicine, General & Internal
Manuscript Type Review
Article Title Biochemical composition of the glomerular extracellular matrix in patients with diabetic kidney disease
Manuscript Source Invited Manuscript
All Author List María M Adeva-Andany and Natalia Carneiro-Freire
ORCID
Author(s) ORCID Number
María M Adeva-Andany http://orcid.org/0000-0002-9997-2568
Natalia Carneiro-Freire http://orcid.org/0000-0003-4404-0541
Funding Agency and Grant Number
Corresponding Author María M Adeva-Andany, MD, PhD, Consultant Physician-Scientist, Nephrology, Hospital Juan Cardona, Pardo Bazán x/n, Ferrol 15406, Spain. madevaa@yahoo.com
Key Words Diabetes; Kidney disease; Glycosaminoglycans; Factor H; Sialic acid; Laminin; Collagen; Fibronectin-1; Extracellular matrix
Core Tip Diabetic kidney disease is associated with profound disturbance in glomerular extracellular matrix (ECM). Understanding the mechanisms that regulate glomerular ECM synthesis and repair may contribute to design therapeutic strategies that improve clinical outcomes. The cytoskeleton inside the foot processes of podocytes is connected to the glomerular basement membrane (GBM) via associated proteins. There is a reciprocal interaction between the cellular cytoskeleton and the extracellular tissue that contribute to regulate ECM composition. Loss of anchor points in the GBM may lead to podocyte detachment. Likewise, alterations in the podocyte cytoskeleton may unfasten the cell and impair the filtration barrier.
Publish Date 2022-07-11 05:53
Citation Adeva-Andany MM, Carneiro-Freire N. Biochemical composition of the glomerular extracellular matrix in patients with diabetic kidney disease. World J Diabetes 2022; 13(7): 498-520
URL https://www.wjgnet.com/1948-9358/full/v13/i7/498.htm
DOI https://dx.doi.org/10.4239/wjd.v13.i7.498
Full Article (PDF) WJD-13-498.pdf
Full Article (Word) WJD-13-498.docx
Manuscript File 75512_Auto_Edited-LS.docx
Answering Reviewers 75512-Answering reviewers.pdf
Audio Core Tip 75512-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 75512-Conflict-of-interest statement.pdf
Copyright License Agreement 75512-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate 75512-Language certificate.pdf
Peer-review Report 75512-Peer-review(s).pdf
Scientific Misconduct Check 75512-Bing-Chang KL-2.jpg
Scientific Editor Work List 75512-Scientific editor work list.pdf