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12/27/2022 10:06:45 AM | Browse: 187 | Download: 352
Publication Name World Journal of Gastroenterology
Manuscript ID 79636
Country/Territory Argentina
Received
2022-09-05 18:01
Peer-Review Started
2022-09-05 18:03
To Make the First Decision
Return for Revision
2022-11-05 07:36
Revised
2022-11-07 20:05
Second Decision
2022-11-25 03:06
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2022-11-27 17:24
Articles in Press
2022-11-27 17:24
Publication Fee Transferred
Edit the Manuscript by Language Editor
2022-12-04 22:46
Typeset the Manuscript
2022-12-20 14:44
Publish the Manuscript Online
2022-12-27 10:06
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Infectious Diseases
Manuscript Type Minireviews
Article Title Molecular mechanisms implicated in SARS-CoV-2 liver tropism
Manuscript Source Invited Manuscript
All Author List Jorge Quarleri and M. Victoria Delpino
ORCID
Author(s) ORCID Number
Jorge Quarleri http://orcid.org/0000-0001-5110-8773
M. Victoria Delpino http://orcid.org/0000-0003-2077-8509
Funding Agency and Grant Number
Corresponding Author M. Victoria Delpino, PhD, Adjunct Professor, Senior Researcher, Institute for Biomedical Research on Retroviruses and AIDS, Faculty of Medical Sciences, National Scientific and Technical Research Council-University of Buenos Aires, Paraguay 2155 Piso 11, Buenos Aires 1121, Argentina. mdelpino@ffyb.uba.ar
Key Words SARS-CoV-2; Viral hepatitis; Non-infectious liver disease; Hyperinflammation
Core Tip Clinical manifestations of coronavirus disease-2019 (COVID-19) may be triggered by the presence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections in the liver. SARS-CoV-2 genomic RNA and its replicative intermediates were found in liver tissues. SARS-CoV-2 causes direct cholangiocyte damage. Systemic inflammation due to COVID-19 correlated with the degree of acute liver injury as revealed by the rise in aspartate aminotransferase levels. SARS-CoV-2 infection increased the risk of morbidity and mortality in patients with a history of advanced liver disease.
Publish Date 2022-12-27 10:06
Citation Quarleri J, Delpino MV. Molecular mechanisms implicated in SARS-CoV-2 liver tropism. World J Gastroenterol 2022; 28(48): 6875-6887
URL https://www.wjgnet.com/1007-9327/full/v28/i48/6875.htm
DOI https://dx.doi.org/10.3748/wjg.v28.i48.6875
Full Article (PDF) WJG-28-6875.pdf
Full Article (Word) WJG-28-6875.docx
Manuscript File 79636-Review-FilipodiaCL.docx
Answering Reviewers 79636-Answering reviewers.pdf
Audio Core Tip 79636-Audio core tip.m4a
Conflict-of-Interest Disclosure Form 79636-Conflict-of-interest statement.pdf
Copyright License Agreement 79636-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate 79636-Language certificate.pdf
Peer-review Report 79636-Peer-review(s).pdf
Scientific Misconduct Check 79636-Bing-Chen YL-2.png
Scientific Editor Work List 79636-Scientific editor work list.pdf