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Articles Published Processes
1/4/2023 5:53:02 AM | Browse: 360 | Download: 822
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Received |
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2022-09-20 17:52 |
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Peer-Review Started |
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2022-09-20 17:55 |
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To Make the First Decision |
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Return for Revision |
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2022-11-05 06:18 |
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Revised |
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2022-11-16 20:32 |
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Second Decision |
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2022-12-14 04:07 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2022-12-14 14:24 |
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Articles in Press |
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2022-12-14 14:24 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2022-12-04 22:55 |
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Typeset the Manuscript |
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2022-12-16 06:16 |
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Publish the Manuscript Online |
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2023-01-04 05:53 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Minireviews |
| Article Title |
Unveiling the biological role of sphingosine-1-phosphate receptor modulators in inflammatory bowel diseases
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Evanthia Tourkochristou, Athanasia Mouzaki and Christos Triantos |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Christos Triantos, FAASLD, MD, PhD, Assistant Professor, Division of Gastroenterology, Department of Internal Medicine, Medical School, University of Patras, Rion, Patras 26504, Greece. chtriantos@hotmail.com |
| Key Words |
Inflammatory bowel disease; Sphingosine-1-phosphate; Intestinal inflammation; Th1/Th17; Sphingosine 1 phosphate; Modulators; Immune responses |
| Core Tip |
Recent literature has highlighted the use of novel oral small molecules, so-called sphingosine-1- phosphate (S1P) receptor modulators, in the therapeutic treatment of inflammatory bowel disease (IBD). Reviews and clinical trials have reported the safety profile and role of S1P modulators in alleviating IBD, but little information is available on their biological function. This is a comprehensive mini-review describing key biological mechanisms beyond the activity of S1P modulators reported in preclinical and clinical studies. The data from this study will contribute to the research field of developing therapeutic strategies in IBD based on the pathogenic biological background. |
| Publish Date |
2023-01-04 05:53 |
| Citation |
Tourkochristou E, Mouzaki A, Triantos C. Unveiling the biological role of sphingosine 1 phosphate receptor modulators in inflammatory bowel diseases. World J Gastroenterol 2023; 29(1): 110-125 |
| URL |
https://www.wjgnet.com/1007-9327/full/v29/i1/110.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v29.i1.110 |
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