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Articles Published Processes
5/26/2023 11:17:59 AM | Browse: 196 | Download: 651
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Received |
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2022-11-09 11:27 |
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Peer-Review Started |
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2022-11-09 11:29 |
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To Make the First Decision |
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Return for Revision |
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2022-12-25 18:38 |
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Revised |
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2023-01-21 14:24 |
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Second Decision |
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2023-04-11 03:03 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2023-04-13 17:49 |
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Articles in Press |
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2023-04-13 17:49 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2023-05-17 08:34 |
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Publish the Manuscript Online |
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2023-05-26 11:17 |
| ISSN |
1948-0210 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Biology |
| Manuscript Type |
Basic Study |
| Article Title |
Stromal cell-derived factor-1α regulates chondrogenic differentiation via activation of the Wnt/β-catenin pathway in mesenchymal stem cells
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Xiao Chen, Xia-Ming Liang, Jia Zheng and Yong-Hui Dong |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Henan Provincial Natural Science Foundation of China |
212300410242 |
| Youth Project Jointly Constructed by Henan Provincial Health Commission and the Ministry |
SBGJ202103008 |
| Henan Young and Middle-aged Health Science and Technology Innovation Excellent Youth Talent Training Project of China |
YXKC2021047 |
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| Corresponding Author |
Yong-Hui Dong, PhD, Professor, Department of Orthopedics, Henan Provincial People’s Hospital, No. 7 Weiwu Road, Jinshui District, Zhengzhou 450003, Henan Province, China. dongyh@zzu.edu.cn |
| Key Words |
Stromal cell-derived factor-1α; Mesenchymal stem cells; Chondrogenic differentiation; Wnt/β-catenin; C-X-C chemokine receptor 4 |
| Core Tip |
In this study, we investigated the effect of stromal cell-derived factor-1α (SDF-1α) on the differentiation of bone marrow mesenchymal stem cells (MSCs) and primary chondrocytes in vitro. We demonstrated that SDF-1α promotes the chondrogenic differentiation of MSCs, and similar results were observed in primary chondrocytes. In addition, SDF-1α also activates the Wnt/β-catenin pathway to regulate chondrocyte hypertrophy and maturation in MSCs. |
| Publish Date |
2023-05-26 11:17 |
| Citation |
Chen X, Liang XM, Zheng J, Dong YH. Stromal cell-derived factor-1α regulates chondrogenic differentiation via activation of the Wnt/β-catenin pathway in mesenchymal stem cells. World J Stem Cells 2023; 15(5): 490-501 |
| URL |
https://www.wjgnet.com/1948-0210/full/v15/i5/490.htm |
| DOI |
https://dx.doi.org/10.4252/wjsc.v15.i5.490 |
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