| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Infectious Diseases |
| Manuscript Type |
Observational Study |
| Article Title |
Changes in characteristics of patients with hepatitis C virus-related cirrhosis from the beginning of the interferon-free era
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Michał Brzdęk, Dorota Zarębska-Michaluk, Piotr Rzymski, Beata Lorenc, Adam Kazek, Magdalena Tudrujek-Zdunek, Justyna Janocha-Litwin, Włodzimierz Mazur, Dorota Dybowska, Hanna Berak, Anna Parfieniuk-Kowerda, Jakub Klapaczyński, Marek Sitko, Barbara Sobala-Szczygieł, Anna Piekarska and Robert Flisiak |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Dorota Zarębska-Michaluk, PhD, Assistant Professor, Professor, Department of Infectious Diseases, Jan Kochanowski Universoty, Radiowa 7, Kielce 25-317, Poland. dorota1010@tlen.pl |
| Key Words |
Hepatitis C; Liver cirrhosis; Direct-acting antivirals; Pangenotypic; Genotype-specific; Epidemiology |
| Core Tip |
Patients with cirrhosis in the course of chronic infection with the hepatitis C virus, in whom the risk of death due to advanced liver disease is the highest, seem to be the greatest beneficiaries of the introduction of therapies with direct-acting antiviral drugs. Our analysis tracking changes in the profile of these patients documents the very high effectiveness and good safety profile from the beginning of the interferon era to the present. |
| Publish Date |
2023-04-07 05:51 |
| Citation |
Brzdęk M, Zarębska-Michaluk D, Rzymski P, Lorenc B, Kazek A, Tudrujek-Zdunek M, Janocha-Litwin J, Mazur W, Dybowska D, Berak H, Parfieniuk-Kowerda A, Klapaczyński J, Sitko M, Sobala-Szczygieł B, Piekarska A, Flisiak R. Changes in characteristics of patients with hepatitis C virus-related cirrhosis from the beginning of the interferon-free era. World J Gastroenterol 2023; 29(13): 2015-2033 |
| URL |
https://www.wjgnet.com/1007-9327/full/v29/i13/2015.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v29.i13.2015 |
