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5/24/2023 9:31:05 AM | Browse: 109 | Download: 241
Publication Name World Journal of Hepatology
Manuscript ID 82379
Country Spain
Received
2022-12-16 21:40
Peer-Review Started
2022-12-16 21:57
To Make the First Decision
Return for Revision
2022-12-31 06:38
Revised
2023-01-07 10:30
Second Decision
2023-04-10 03:10
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2023-04-10 08:18
Articles in Press
2023-04-10 08:18
Publication Fee Transferred
Edit the Manuscript by Language Editor
2023-03-30 22:10
Typeset the Manuscript
2023-05-17 07:47
Publish the Manuscript Online
2023-05-24 09:31
ISSN 1948-5182 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Observational Study
Article Title Liver steatosis in patients with rheumatoid arthritis treated with methotrexate is associated with body mass index
Manuscript Source Invited Manuscript
All Author List Agustin Castiella, Luis Lopez-Dominguez, Maria J Sanchez-Iturri, Iratxe Urreta, Andrea De Diego, Joaquin Belzunegui and Eva Zapata
ORCID
Author(s) ORCID Number
Agustin Castiella http://orcid.org/0000-0003-3179-9233
Luis Lopez-Dominguez http://orcid.org/0000-0001-9097-4164
Maria J Sanchez-Iturri http://orcid.org/0000-0001-6018-1569
Iratxe Urreta http://orcid.org/0000-0003-0498-6033
Andrea De Diego http://orcid.org/0000-0001-6092-9776
Joaquin Belzunegui http://orcid.org/0000-0002-8955-6130
Eva Zapata http://orcid.org/0000-0002-5412-619X
Funding Agency and Grant Number
Corresponding Author Agustin Castiella, MD, PhD, Staff Physician, Department of Gastroenterology Service, Donostia University Hospital, Servicio Digestivo, Donostia 20014, Spain. agustincastiella@yahoo.es
Key Words Methotrexate; Rheumatoid arthritis; Liver steatosis; Liver fibrosis; Transient elastography; Computed attenuation parameter
Core Tip Methotrexate (MTX) is the cornerstone of treatment for rheumatoid arthritis and has been associated with the development of liver fibrosis (LF) and liver steatosis (LS). The objective of this work was to study if LS in patients with rheumatoid arthritis treated with MTX and determine the association with body mass index, MTX cumulative dose, sex, LF, and metabolic syndrome. We concluded that LS in patients with rheumatoid arthritis on MTX treatment was not related to MTX-cumulative dose, LF, the male sex, or metabolic syndrome. In our study, body mass index was significantly associated with LS in these patients.
Publish Date 2023-05-24 09:31
Citation Castiella A, Lopez-Dominguez L, Sanchez-Iturri MJ, Urreta I, De Diego A, Belzunegui J, Zapata E. Liver steatosis in patients with rheumatoid arthritis treated with methotrexate is associated with body mass index. World J Hepatol 2023; 15(5): 699-706
URL https://www.wjgnet.com/1948-5182/full/v15/i5/699.htm
DOI https://dx.doi.org/10.4254/wjh.v15.i5.699
Full Article (PDF) WJH-15-699-with-cover.pdf
Full Article (Word) WJH-15-699.docx
Manuscript File 82379_Auto_Edited-JRF-Filipodia CL-JLW.docx
Answering Reviewers 82379-Answering reviewers.pdf
Audio Core Tip 82379-Audio core tip.m4a
Biostatistics Review Certificate 82379-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 82379-Conflict-of-interest statement.pdf
Copyright License Agreement 82379-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s) 82379-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 82379-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 82379-Language certificate.pdf
Supplementary Material 82379-Supplementary material.pdf
Peer-review Report 82379-Peer-review(s).pdf
Scientific Misconduct Check 82379-Bing-Fan JR-2.png
Scientific Editor Work List 82379-Scientific editor work list.pdf