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Publication Name World Journal of Orthopedics
Manuscript ID 8713
Country of Manuscript Source Germany
Received
2014-01-03 16:54
Peer-Review Started
2014-01-03 21:20
To Make the First Decision
2014-02-27 10:01
Return for Revision
2014-03-10 20:28
Revised
2014-03-14 19:39
Second Decision
2014-06-11 12:26
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2014-06-11 12:34
Articles in Press
2014-06-11 13:11
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2014-08-11 08:38
Publish the Manuscript Online
2014-08-20 20:37
ISSN 2218-5836 (online)
Open Access
Copyright
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Specialty Orthopedics
Manuscript type Topic Highlights
Article Title Enhanced microfracture techniques in cartilage knee surgery: Fact or fiction?
Manuscript Source Invited Manuscript
All Author List Stefan Bark, Tomasz Piontek, Peter Behrens, Sabreen Mkalaluh, Deike Varoga and Justus Gille
Funding Agency and Grant Number
Correspondence To Bark Stefan, MD, Department of Trauma and Reconstructive Surgery, University of Schleswig-Holstein, Ratzeburger Allee 160, 23538 Campus Luebeck, Germany. stefan.bark@uksh.de
Keywords Cartilage; Microfracture; Autologous; Matrix-Induced Chondrogenesis; Knee; Chondro-Gide?
Core Tip Articular cartilage has a limited healing potential which presents a well-known circumstance in orthopedic surgery. This fact has led to a variety of surgical techniques for treating articular defects and currently the microfracturing presents the most commonly used procedure. The aim of this article is to give an overview about actual studies regarding microfracture and the AMIC? technique in cartilage knee surgery and to show recent developments.This article reviews the pre-clinical rationale of microfractures and AMIC?, presents clinical studies and shows the advantages and disadvantages of these widely used techniques. Material and Methods PubMed and the Cochrane database were searched to identify relevant studies. We used a comprehensive search strategy with no date or language restrictions to locate studies that examined the AMIC? technique and microfracture. Search keywords included cartilage, microfracture, AMIC?, knee, Chondro-Gide?. Besides this, we included our own experiences and study authors were contacted if more and non published data were needed. Results Both cartilage repair techniques represent an effective and safe method of treating full-thickness chondral defects of the knee in selected cases. While results after microfracture deteriorate with time, mid-term results after AMIC? seem to be enduring. Conclusion Randomized studies with long-term follow-up are needed whether the grafted area will maintain functional improvement and structural integrity over time.
Publish Date 2014-08-20 20:37
Citation Bark S, Piontek T, Peter B, Mkalaluh S, Varoga D, Gille J. Enhanced microfracture techniques in cartilage knee surgery: Fact or fiction? World J Orthop 2014; 5(4): 444-449
Url http://www.wjgnet.com/2218-5836/full/v5/i4/444.htm
DOI http://dx.doi.org/10.5312/wjo.v5.i4.444
Full Article (PDF) WJO-5-444.pdf
Full Article (Word) WJO-5-444.doc
Manuscript File 8713-Review.docx
Answering Reviewers 8713-Answering reviewers.pdf
Copyright License Agreement 8713-Copyright assignment.pdf
Peer-review Report 8713-Peer review(s).pdf
Scientific Misconduct Check 8713-CorssCheck.jpg
Scientific Editor Work List 8713-Scientific editor work list.pdf