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2/6/2024 6:16:03 AM | Browse: 115 | Download: 77
Publication Name World Journal of Psychiatry
Manuscript ID 90110
Country/Territory China
Received
2023-11-23 12:04
Peer-Review Started
2023-11-23 12:05
To Make the First Decision
Return for Revision
2023-12-06 03:12
Revised
2023-12-13 16:12
Second Decision
2024-01-08 03:09
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2024-01-08 08:32
Articles in Press
2024-01-08 08:32
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2024-02-01 13:27
Publish the Manuscript Online
2024-02-06 06:16
ISSN 2220-3206 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Neuroimaging
Manuscript Type Retrospective Study
Article Title Neuropathological characteristics of abnormal white matter functional signaling in adolescents with major depression
Manuscript Source Unsolicited Manuscript
All Author List Xin-Lin Huang, Ju Gao, Yong-Ming Wang, Feng Zhu, Jing Qin, Qian-Nan Yao, Xiao-Bin Zhang and Hong-Yan Sun
ORCID
Author(s) ORCID Number
Xin-Lin Huang http://orcid.org/0009-0005-8660-5469
Xiao-Bin Zhang http://orcid.org/0000-0002-0577-5951
Hong-Yan Sun http://orcid.org/0009-0009-2030-1103
Funding Agency and Grant Number
Funding Agency Grant Number
the Suzhou Clinical Medical Center for Mood Disorders Szlcyxzx202109
Jiangsu Provincial Department of Science and Technology for Social Development-General Project BE2022735
Corresponding Author Hong-Yan Sun, MD, PhD, Chief Doctor, Department of Radiology, The Affiliated Guangji Hospital of Soochow University, No. 11 Guangqian Road, Suzhou 215137, Jiangsu Province, China. hoya12@126.com
Key Words White matter; Regional homogeneity; The fractional amplitude of low-frequency fluctuations; Independent component analysis; Adolescents; Major depression disorders
Core Tip This groundbreaking study investigates white matter (WM) functional signals in adolescents with major depressive disorder (MDD), an area often overlooked in research. Utilizing advanced imaging techniques, the study identifies specific abnormalities in WM signals, revealing decreased fractional amplitude of low frequency fluctuations in key regions and altered regional homogeneity and independent component analysis patterns. Notably, these changes correlate with suicidality scales, indicating a potential link between WM anomalies and severity of depression. The study pioneers a crucial shift in understanding MDD's neuropathogenesis, offering novel insights and support for future research and predictive measures.
Publish Date 2024-02-06 06:16
Citation Huang XL, Gao J, Wang YM, Zhu F, Qin J, Yao QN, Zhang XB, Sun HY. Neuropathological characteristics of abnormal white matter functional signaling in adolescents with major depression. World J Psychiatry 2024; 14(2): 276-286
URL https://www.wjgnet.com/2220-3206/full/v14/i2/276.htm
DOI https://dx.doi.org/10.5498/wjp.v14.i2.276
Full Article (PDF) WJP-14-276-with-cover.pdf
Full Article (Word) WJP-14-276.docx
Manuscript File 90110_Auto_Edited-JLW.docx
Answering Reviewers 90110-Answering reviewers.pdf
Audio Core Tip 90110-Audio core tip.mp3
Biostatistics Review Certificate 90110-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 90110-Conflict-of-interest statement.pdf
Copyright License Agreement 90110-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 90110-Grant application form(s).pdf
Signed Informed Consent Form(s) or Document(s) 90110-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 90110-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 90110-Language certificate.pdf
Peer-review Report 90110-Peer-review(s).pdf
Scientific Misconduct Check 90110-Bing-Li L-2.png
Scientific Editor Work List 90110-Scientific editor work list.pdf