| Category |
Cardiac & Cardiovascular Systems |
| Manuscript Type |
Minireviews |
| Article Title |
Nuclear imaging in detection and monitoring of cardiotoxicity
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Carmen D’Amore, Paola Gargiulo, Stefania Paolillo, Angela Maria Pellegrino, Tiziana Formisano, Antonio Mariniello, Giuseppe Della Ratta, Elisabetta Iardino, Marianna D’Amato, Lucia La Mura, Irma Fabiani, Flavia Fusco and Pasquale Perrone Filardi |
| Funding Agency and Grant Number |
|
| Corresponding Author |
Pasquale Perrone Filardi, MD, PhD, Department of Advanced Biomedical Sciences, Federico II University, Via Pansini, 5, 80131 Naples, Italy. fpperron@unina.it |
| Key Words |
Cardiotoxicity; Cardiac nuclear imaging; Early diagnosis; Scintigraphy; Positron emission tomography |
| Core Tip |
Cardiomyopathy is a potential complication of various anticancer drugs, such as anthracyclines and biological therapy. Left ventricular dysfunction is the most common manifestation of cardiotoxicity and is monitored with left ventricular ejection fraction measurement, but it is a late manifestation of myocardial injury. Thus, the cardiologist and oncologist should collaborate to identify new non-invasive techniques to detect cardiac dysfunction at an early and potentially reversible stage, before the onset of clinical manifestation. To achieve this aim, nuclear imaging techniques may offer good future perspectives for early detection of myocardial damage using novel molecular tracers. |
| Publish Date |
2014-07-31 11:53 |
| Citation |
D’Amore C, Gargiulo P, Paolillo S, Pellegrino AM, Formisano T, Mariniello A, Della Ratta G, Iardino E, D’Amato M, La Mura L, Fabiani I, Fusco F, Perrone Filardi P. Nuclear imaging in detection and monitoring of cardiotoxicity. World J Radiol 2014; 6(7): 486-492 |
| URL |
http://www.wjgnet.com/1949-8470/full/v6/i7/486.htm |
| DOI |
http://dx.doi.org/10.4329/wjr.v6.i7.486 |
