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11/24/2021 9:54:22 AM | Browse: 267 | Download: 341
Publication Name World Journal of Hepatology
Manuscript ID 65083
Country India
Received
2021-02-27 17:51
Peer-Review Started
2021-02-27 17:53
To Make the First Decision
Return for Revision
2021-05-02 23:58
Revised
2021-05-07 20:51
Second Decision
2021-08-20 02:33
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2021-08-20 06:20
Articles in Press
2021-08-20 06:20
Publication Fee Transferred
Edit the Manuscript by Language Editor
2021-10-03 21:53
Typeset the Manuscript
2021-11-19 02:19
Publish the Manuscript Online
2021-11-24 09:54
ISSN 1948-5182 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Review
Article Title Chelation therapy in liver diseases of childhood: Current status and response
Manuscript Source Invited Manuscript
All Author List Jayendra Seetharaman and Moinak Sen Sarma
ORCID
Author(s) ORCID Number
Jayendra Seetharaman http://orcid.org/0000-0001-7991-6975
Moinak Sen Sarma http://orcid.org/0000-0003-2015-4069
Funding Agency and Grant Number
Corresponding Author Moinak Sen Sarma, MBBS, MD, Assistant Professor, Department of Pediatric Gastroenterology, Sanjay Gandhi Post-graduate Institute of Medical Sciences, Raebareli Road, Lucknow 226014, Uttar Pradesh, India. moinaksen@gmail.com
Key Words Wilson’s disease; D-Penicillamine; Trientine; Indian childhood cirrhosis; Deferoxamine; Deferasirox; Hemochromatosis
Core Tip Chelation forms the most important part of management of certain liver diseases in children. In Wilson's disease and secondary hemochromatosis related to transfusion, chelation is well established treatment modality with proven efficacy. In other diseases like copper associated childhood cirrhosis and neonatal hemochromatosis the role of chelation is doubtful. In Herediatary hemochromatosis, chelation is recommended as alternative therapy. The selection of chelating agents for treatment depends on the efficacy, feasibility and risk of adverse effects known from literature. The review discusses the concepts of chelation and reviews the literature to assess the role of chelation in treatment of various pediatric liver diseases.
Publish Date 2021-11-24 09:54
Citation Seetharaman J, Sarma MS. Chelation therapy in liver diseases of childhood: Current status and response. World J Hepatol 2021; 13(11): 1552-1567
URL https://www.wjgnet.com/1948-5182/full/v13/i11/1552.htm
DOI https://dx.doi.org/10.4254/wjh.v13.i11.1552
Full Article (PDF) WJH-13-1552.pdf
Full Article (Word) WJH-13-1552.docx
Manuscript File 65083-Review-FilipodiaCL.docx
Answering Reviewers 65083-Answering reviewers.pdf
Audio Core Tip 65083-Audio core tip.aac
Conflict-of-Interest Disclosure Form 65083-Conflict-of-interest statement.pdf
Copyright License Agreement 65083-Copyright license agreement.pdf
Peer-review Report 65083-Peer-review(s).pdf
Scientific Misconduct Check 65083-Scientific misconduct check.pdf
Scientific Editor Work List 65083-Scientific editor work list.pdf