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Articles Published Processes
11/6/2021 4:43:07 AM | Browse: 386 | Download: 515
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Received |
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2021-05-14 08:13 |
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Peer-Review Started |
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2021-05-14 08:16 |
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To Make the First Decision |
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Return for Revision |
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2021-07-14 04:53 |
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Revised |
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2021-07-21 10:38 |
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Second Decision |
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2021-08-30 03:32 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2021-08-30 09:31 |
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Articles in Press |
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2021-08-30 09:31 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2021-11-02 03:06 |
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Publish the Manuscript Online |
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2021-11-06 04:43 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Basic Study |
| Article Title |
Circulating tumor DNA dynamics analysis in a xenograft mouse model with esophageal squamous cell carcinoma
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Hiroyuki Terasawa, Hideaki kinugasa, Kazuhiro Nouso, Shumpei Yamamoto, Mami Hirai, Takehiro Tanaka, Akinobu Takaki and Hiroyuki Okada |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| JSPS KAKENHI (19k17433) |
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| Corresponding Author |
Hideaki kinugasa, MD, PhD, Doctor, Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 2-5-1 Shikata-Cho Kita-Ku, Okayama 7008558, Japan. gyacy14@gmail.com |
| Key Words |
Liquid biopsy; Circulating tumor DNA; Xenograft; Esophageal squamous cell carcinoma; Dynamics of circulating tumor DNA |
| Core Tip |
We clarified the origin and dynamics of circulating tumor DNA (ctDNA), showing that not only tumor invasion but also tumor volume was an important factor. The possibility of detecting ctDNA in early-stage cancers with shallow depth was demonstrated. Also, ctDNA could be measured at 1 d after tumor resection to evaluate the residuals, and the half-life of ctDNA was estimated to be 1.8-3.2 h. |
| Publish Date |
2021-11-06 04:43 |
| Citation |
Terasawa H, Kinugasa H, Nouso K, Yamamoto S, Hirai M, Tanaka T, Takaki A, Okada H. Circulating tumor DNA dynamics analysis in a xenograft mouse model with esophageal squamous cell carcinoma. World J Gastroenterol 2021; 27(41): 7134-7143 |
| URL |
https://www.wjgnet.com/1007-9327/full/v27/i41/7134.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v27.i41.7134 |
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