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Articles Published Processes
12/27/2023 12:41:39 PM | Browse: 80 | Download: 264
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Received |
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2023-09-13 08:50 |
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Peer-Review Started |
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2023-09-13 08:50 |
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To Make the First Decision |
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Return for Revision |
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2023-09-28 09:59 |
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Revised |
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2023-10-18 13:53 |
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Second Decision |
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2023-11-14 09:33 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2023-11-21 07:13 |
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Articles in Press |
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2023-11-21 07:13 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2023-12-22 03:40 |
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Publish the Manuscript Online |
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2023-12-27 12:41 |
ISSN |
1948-9366 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Basic Study |
Article Title |
Mutational separation and clinical outcomes of TP53 and CDH1 in gastric cancer
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Manuscript Source |
Unsolicited Manuscript |
All Author List |
He-Li Liu, Huan Peng, Chang-Hao Huang, Hai-Yan Zhou and Jie Ge |
ORCID |
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Funding Agency and Grant Number |
Funding Agency |
Grant Number |
Guangdong Yiyang Healthcare Charity Foundation |
JZ2022014 |
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Corresponding Author |
Jie Ge, MD, Attending Doctor, Department of Gastrointestinal Surgery, Xiangya Hospital, Central South University, No. 87 Xiangya Road, Kaifu District, Changsha 410008, Hunan Province, China. gejie@csu.edu.cn |
Key Words |
Gastric cancer; TP53 mutation; CDH1 mutation; Clinical outcome; Somatic mutation; Diffuse gastric cancer |
Core Tip |
Mutational separation of TP53 and CDH1 in gastric cancer (GC) reveals their distinct mechanisms. TP53 mutations are associated with advanced-stage tumors and poor prognoses, whereas CDH1 mutations are associated with diffuse GC. This study highlights the heterogeneity of GC and provides insights into potential targeted therapies based on specific mutation patterns. Understanding the mutational landscape of TP53 and CDH1 can contribute to personalized treatment approaches for patients with GC. |
Publish Date |
2023-12-27 12:41 |
Citation |
Liu HL, Peng H, Huang CH, Zhou HY, Ge J. Mutational separation and clinical outcomes of TP53 and CDH1 in gastric cancer. World J Gastrointest Surg 2023; 15(12): 2855-2865 |
URL |
https://www.wjgnet.com/1948-9366/full/v15/i12/2855.htm |
DOI |
https://dx.doi.org/10.4240/wjgs.v15.i12.2855 |
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