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12/27/2023 12:41:39 PM | Browse: 80 | Download: 264
Publication Name World Journal of Gastrointestinal Surgery
Manuscript ID 87400
Country China
Received
2023-09-13 08:50
Peer-Review Started
2023-09-13 08:50
To Make the First Decision
Return for Revision
2023-09-28 09:59
Revised
2023-10-18 13:53
Second Decision
2023-11-14 09:33
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2023-11-21 07:13
Articles in Press
2023-11-21 07:13
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2023-12-22 03:40
Publish the Manuscript Online
2023-12-27 12:41
ISSN 1948-9366 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Basic Study
Article Title Mutational separation and clinical outcomes of TP53 and CDH1 in gastric cancer
Manuscript Source Unsolicited Manuscript
All Author List He-Li Liu, Huan Peng, Chang-Hao Huang, Hai-Yan Zhou and Jie Ge
ORCID
Author(s) ORCID Number
He-Li Liu http://orcid.org/0000-0002-3443-6174
Huan Peng http://orcid.org/0000-0002-3073-5708
Chang-Hao Huang http://orcid.org/0009-0000-6755-6618
Hai-Yan Zhou http://orcid.org/0000-0002-2860-1858
Jie Ge http://orcid.org/0000-0002-4186-4740
Funding Agency and Grant Number
Funding Agency Grant Number
Guangdong Yiyang Healthcare Charity Foundation JZ2022014
Corresponding Author Jie Ge, MD, Attending Doctor, Department of Gastrointestinal Surgery, Xiangya Hospital, Central South University, No. 87 Xiangya Road, Kaifu District, Changsha 410008, Hunan Province, China. gejie@csu.edu.cn
Key Words Gastric cancer; TP53 mutation; CDH1 mutation; Clinical outcome; Somatic mutation; Diffuse gastric cancer
Core Tip Mutational separation of TP53 and CDH1 in gastric cancer (GC) reveals their distinct mechanisms. TP53 mutations are associated with advanced-stage tumors and poor prognoses, whereas CDH1 mutations are associated with diffuse GC. This study highlights the heterogeneity of GC and provides insights into potential targeted therapies based on specific mutation patterns. Understanding the mutational landscape of TP53 and CDH1 can contribute to personalized treatment approaches for patients with GC.
Publish Date 2023-12-27 12:41
Citation Liu HL, Peng H, Huang CH, Zhou HY, Ge J. Mutational separation and clinical outcomes of TP53 and CDH1 in gastric cancer. World J Gastrointest Surg 2023; 15(12): 2855-2865
URL https://www.wjgnet.com/1948-9366/full/v15/i12/2855.htm
DOI https://dx.doi.org/10.4240/wjgs.v15.i12.2855
Full Article (PDF) WJGS-15-2855-with-cover.pdf
Full Article (Word) WJGS-15-2855.docx
The ARRIVE Guidelines 87400-The ARRIVE guidelines.pdf
Manuscript File 87400_Auto_Edited-JLW.docx
Answering Reviewers 87400-Answering reviewers.pdf
Audio Core Tip 87400-Audio core tip.m4a
Biostatistics Review Certificate 87400-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 87400-Conflict-of-interest statement.pdf
Copyright License Agreement 87400-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 87400-Grant application form(s).pdf
Institutional Animal Care and Use Committee Approval Form or Document 87400-Institutional animal care and use committee statement.pdf
Institutional Review Board Approval Form or Document 87400-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 87400-Language certificate.pdf
Peer-review Report 87400-Peer-review(s).pdf
Scientific Misconduct Check 87400-Bing-Lin C-2.png
Scientific Editor Work List 87400-Scientific editor work list.pdf