Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	90781
Country	China

Received	2023-12-22 01:34
Peer-Review Started	2023-12-22 01:34
To Make the First Decision
Return for Revision	2024-01-09 08:29
Revised	2024-01-26 06:36
Second Decision	2024-02-18 01:51
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2024-02-18 03:41
Articles in Press	2024-02-18 03:41
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-03-21 13:04
Publish the Manuscript Online	2024-04-11 02:23

ISSN	1948-5204 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Gastroenterology & Hepatology
Manuscript Type	Basic Study
Article Title	Upregulated lncRNA PRNT promotes progression and oxaliplatin resistance of colorectal cancer cells by regulating HIPK2 transcription
Manuscript Source	Unsolicited Manuscript
All Author List	Sai-Nan Li, Shan Yang, Hao-Qi Wang, Tian-Li Hui, Meng Cheng, Xi Zhang, Bao-Kun Li and Gui-Ying Wang
ORCID	Author(s) ORCID Number Gui-Ying Wang http://orcid.org/0009-0004-5540-7016
Funding Agency and Grant Number	Funding Agency Grant Number Hebei Provincial Health Commission Youth Science and Technology Project 20210027
Corresponding Author	Gui-Ying Wang, PhD, Surgeon, The Second Department of Surgery, The Fourth Hospital of Hebei Medical University, No. 12 Jiankang Road, Shijiazhuang 050011, Hebei Province, China. hebeiwangguiying@163.com
Key Words	Colorectal cancer; Oxaliplatin resistance; Prion protein testis specific; Zinc finger protein 184; Homeodomain interacting protein kinase 2
Core Tip	The revelation that long noncoding RNA prion protein testis specific, which is overexpressed in oxaliplatin-resistant colorectal cancer (CRC) cells, regulates the expression of homeodomain interacting protein kinase 2 by sponging transcription factor zinc finger protein 184 unveils a promising target for enhancing the efficacy of chemotherapy. This mechanistic insight could lead to the development of novel therapeutic strategies to combat resistance in CRC treatments.
Publish Date	2024-04-11 02:23
Citation	Li SN, Yang S, Wang HQ, Hui TL, Cheng M, Zhang X, Li BK, Wang GY. Upregulated lncRNA PRNT promotes progression and oxaliplatin resistance of colorectal cancer cells by regulating HIPK2 transcription. World J Gastrointest Oncol 2024; 16(4): 1564-1577
URL	https://www.wjgnet.com/1948-5204/full/v16/i4/1564.htm
DOI	https://dx.doi.org/10.4251/wjgo.v16.i4.1564

Full Article (PDF)	WJGO-16-1564-with-cover.pdf
The ARRIVE Guidelines	90781-The ARRIVE guidelines.pdf
Manuscript File	90781_Auto_Edited-YJP.docx
Answering Reviewers	90781-Answering reviewers.pdf
Audio Core Tip	90781-Audio core tip.mp3
Biostatistics Review Certificate	90781-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	90781-Conflict-of-interest statement.pdf
Copyright License Agreement	90781-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	90781-Grant application form(s).pdf
Institutional Animal Care and Use Committee Approval Form or Document	90781-Institutional animal care and use committee statement.pdf
Institutional Review Board Approval Form or Document	90781-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate	90781-Language certificate.pdf
Peer-review Report	90781-Peer-review(s).pdf
Scientific Misconduct Check	90781-CrossCheck.png
Scientific Misconduct Check	90781-Google-Gong ZM-2.png
Scientific Editor Work List	90781-Scientific editor work list.pdf