Publication Name	World Journal of Transplantation
Manuscript ID	55261
Country	Italy

Received	2020-03-08 14:55
Peer-Review Started	2020-03-08 14:56
To Make the First Decision
Return for Revision	2020-04-22 21:14
Revised	2020-05-17 13:37
Second Decision	2020-05-28 09:36
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2020-05-29 20:35
Articles in Press	2020-05-29 20:35
Publication Fee Transferred
Edit the Manuscript by Language Editor	2020-06-01 20:05
Typeset the Manuscript	2020-07-20 00:09
Publish the Manuscript Online	2020-07-23 05:10

ISSN	2220-3230 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Transplantation
Manuscript Type	Review
Article Title	Current protocols and outcomes of ABO-incompatible kidney transplantation
Manuscript Source	Invited Manuscript
All Author List	Maurizio Salvadori and Aris Tsalouchos
Funding Agency and Grant Number
Corresponding Author	Maurizio Salvadori, MD, Professor, Department of Transplantation Renal Unit, Careggi University Hospital, Viale Pieraccini 18, Florence 50139, Italy. maurizio.salvadori1@gmail.com
Key Words	ABO-incompatible transplants; Desensitization strategies; Immunological aspects; B cell depletion; Immunomodulation; Apheresis techniques
Core Tip	Renal transplantation from living donors across different and incompatible ABO-incompatible immunological barriers has become safe and effective in recent years because our improved knowledge of the immune system and the availability of new drugs. Recipient desensitization and paired kidney donation are the two strategies adopted. Among the desensitization tools, a relevant role has Rituximab that allowed avoiding splenectomy, the apheretic techniques to eliminate the preformed alloantibodies and high dose intravenous immunoglobulins to improve the immunomodulation. Several points still remain to be better clarified, but recently the outcomes of these transplants have attained those of standard transplantation.
Publish Date	2020-07-23 05:10
Citation	Salvadori M, Tsalouchos A. Current protocols and outcomes of ABO-incompatible kidney transplantation. World J Transplant 2020; 10(7): 191-205
URL	https://www.wjgnet.com/2220-3230/full/v10/i7/191.htm
DOI	https://dx.doi.org/10.5500/wjt.v10.i7.191

Full Article (PDF)	WJT-10-191.pdf
Full Article (Word)	WJT-10-191.docx
Manuscript File	55261-Review-Filipodia.docx
Answering Reviewers	55261-Answering reviewers.pdf
Audio Core Tip	55261-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	55261-Conflict-of-interest statement.pdf
Copyright License Agreement	55261-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	55261-Language certificate.pdf
Peer-review Report	55261-Peer-review(s).pdf
Scientific Misconduct Check	55261-Bing-Zhang L-2.png
Scientific Misconduct Check	55261-Scientific misconduct check.pdf
Scientific Editor Work List	55261-Scientific editor work list.pdf