Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	64614
Country	Japan

Received	2021-02-21 08:56
Peer-Review Started	2021-02-21 08:59
First Decision by Editorial Office Director	2021-05-08 04:11
Return for Revision	2021-05-08 04:11
Revised	2021-06-03 13:45
Publication Fee Transferred
Second Decision by Editor	2021-08-11 03:25
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2021-08-11 07:37
Articles in Press	2021-08-11 07:37
Edit the Manuscript by Language Editor
Typeset the Manuscript	2021-09-02 08:25
Publish the Manuscript Online	2021-09-10 12:09

ISSN	1948-5204 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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Category	Oncology
Manuscript Type	Review
Article Title	Involvement of integrin-activating peptides derived from tenascin-C in colon cancer progression
Manuscript Source	Invited Manuscript
All Author List	Motomichi Fujita, Hideo Suzuki and Fumio Fukai
Funding Agency and Grant Number
Corresponding Author	Fumio Fukai, PhD, Professor, Department of Molecular Patho-Physiology, Tokyo University of Science, 2641 Yamazaki, Noda 278-8510, Chiba, Japan. fukai@rs.noda.tus.ac.jp
Key Words	Tenascin-C; TNIIIA2; Beta1-integrin; Integrin activation; Colitis-associated colorectal cancer; Colon cancer
Core Tip	Exposure of the cryptic functional site TNIIIA2 from the Tenascin-C (TNC) molecule and its potent and sustained activation of beta1-integrins appear to be associated with the development of colon cancer and its malignant progression. Inhibition of the biological function of TNIIIA2 derived from TNC molecule may be a promising strategy for the prevention and treatment of colon cancer.
Publish Date	2021-09-10 12:09
Citation	Fujita M, Suzuki H, Fukai F. Involvement of integrin-activating peptides derived from tenascin-C in colon cancer progression. World J Gastrointest Oncol 2021; 13(9): 980-994
URL	https://www.wjgnet.com/1948-5204/full/v13/i9/980.htm
DOI	https://dx.doi.org/10.4251/wjgo.v13.i9.980

Full Article (PDF)	WJGO-13-980.pdf
Full Article (Word)	WJGO-13-980.docx
Manuscript File	64614_Auto_Edited-JPY.docx
Answering Reviewers	64614-Answering reviewers.pdf
Audio Core Tip	64614-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	64614-Conflict-of-interest statement.pdf
Copyright License Agreement	64614-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	64614-Language certificate.pdf
Peer-review Report	64614-Peer-review(s).pdf
Scientific Misconduct Check	64614-Bing-Wang JL-1.jpg
Scientific Misconduct Check	64614-Bing-Fan JR-2.png
Scientific Misconduct Check	64614-Scientific misconduct check.pdf
Scientific Editor Work List	64614-Scientific editor work list.pdf
CrossCheck Report	64614-CrossCheck report.pdf
CrossCheck Report	64614-CrossCheck.png