| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
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| Permissions |
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Transplantation |
| Manuscript Type |
Retrospective Study |
| Article Title |
Outcomes of ABO-incompatible liver transplantation in end-stage liver disease patients co-infected with hepatitis B and human immunodeficiency virus
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Jian-Xin Tang, Kang-Jun Zhang, Tai-Shi Fang, Rui-Hui Weng, Zi-Ming Liang, Xu Yan, Xin Jin, Lin-Jie Xie, Xin-Chen Zeng and Dong Zhao |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| The Third People's Hospital of Shenzhen Scientific Research Project |
G2021008 |
| The Third People's Hospital of Shenzhen Scientific Research Project |
G2022008 |
| Shenzhen Key Medical Discipline Construction Fund |
SZXK079 |
| Shenzhen Science and Technology Research and Development Fund |
JCYJ20210324131809027 |
| Shenzhen Science and Technology Research and Development Fund |
JCYJ20220530163011026 |
|
| Corresponding Author |
Dong Zhao, MD, Chief Doctor, Professor, Surgeon, Department of Liver Surgery and Organ Transplantation Center, The Third People's Hospital of Shenzhen, No. 29 Bulan Road, Longgang District, Shenzhen 518000, Guangdong Province, China. zdong1233@126.com |
| Key Words |
ABO incompatibility liver transplantation; Human immunodeficiency virus; Hepatitis B virus; End-stage liver disease; Immunosuppression |
| Core Tip |
The outcome of human immunodeficiency virus (HIV)-hepatitis B virus (HBV) coinfected patients referred for ABO-incompatible liver transplantation (LT) (ABOi-LT) is unknown. We reported two Chinese HIV-HBV coinfected patients with end-stage liver disease (ESLD) who underwent A to O brain-dead donor LT and reviewed the literature on HIV-HBV coinfected patients treated with ABO-compatible LT. At intermediate-term follow-up, patients showed undetectable HIV viral load, CD4(+) T cell counts greater than 150 cells/μL, no HBV recurrence, and stable liver function. Both patients survived at 36-42 months of follow-up. This is the first report of ABOi-LT in HIV-HBV recipients with good intermediate-term outcomes, suggesting that ABOi-LT may be feasible and safe for HIV-HBV coinfected patients with ESLD. |
| Publish Date |
2023-03-17 06:20 |
| Citation |
Tang JX, Zhang KJ, Fang TS, Weng RH, Liang ZM, Yan X, Jin X, Xie LJ, Zeng XC, Zhao D. Outcomes of ABO-incompatible liver transplantation in end-stage liver disease patients co-infected with hepatitis B and human immunodeficiency virus. World J Gastroenterol 2023; 29(11): 1745-1756 |
| URL |
https://www.wjgnet.com/1007-9327/full/v29/i11/1745.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v29.i11.1745 |
