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5/7/2023 9:19:03 AM | Browse: 127 | Download: 335
Publication Name World Journal of Gastroenterology
Manuscript ID 82578
Country China
Received
2022-12-26 04:59
Peer-Review Started
2022-12-26 05:01
To Make the First Decision
Return for Revision
2023-02-08 01:17
Revised
2023-02-17 14:57
Second Decision
2023-04-13 03:05
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2023-04-13 09:04
Articles in Press
2023-04-13 09:04
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2023-04-21 03:27
Publish the Manuscript Online
2023-05-07 07:47
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Basic Study
Article Title Establishment and characterization of a new human ampullary carcinoma cell line, DPC-X1
Manuscript Source Unsolicited Manuscript
All Author List Hao Xu, Chang-Peng Chai, Xin Miao, Huan Tang, Jin-Jing Hu, Hui Zhang and Wen-Ce Zhou
Funding Agency and Grant Number
Funding Agency Grant Number
National Natural Science Foundation of China 82260555
Gansu Provincial Science and Technology Plan 1606RJZA139
Gansu Provincial Science and Technology Plan 21JR11RA096
Gansu Provincial Science and Technology Plan 21JR1RA099
Gansu Provincial Science and Technology Plan 21JR1RA113
Gansu Health Industry Project GSWSKY2020-21
Traditional Chinese Medicine Scientific Research Project of Gansu Province GZKP-2020-28
Talent Innovation and Entrepreneurship Project of Lanzhou 2020-RC-46
Intra-Hospital Fund of the First Hospital of Lanzhou University ldyyyn2019-97
Corresponding Author Hao Xu, Doctor, MD, Associate Chief Physician, Surgeon, The Forth Department of General Surgery, The First Hospital of Lanzhou University, No. 1 Donggang West Road, Lanzhou 730000, Gansu Province, China. amoyxu@126.com
Key Words Ampullary carcinoma; Cell line; Xenograft; Drug resistance
Core Tip A new ampullary carcinoma cell line has been established, making up for the shortage of Chinese ampullary carcinoma cell lines. And this is the the first study to report a mixed-type ampullary carcinoma cell line. The cell line inoculated into BALB/c nude mice can quickly form xenograft tumors. It is an excellent model for studying the mechanisms of invasion, metastasis and other mechanisms of ampullary carcinoma. The cell line is sensitive to oxaliplatin and paclitaxel but is naturally resistant to gemcitabine and fluorouracil, which can be used for drug resistance mechanism research and new drug development.
Publish Date 2023-05-07 07:47
Citation Xu H, Chai CP, Miao X, Tang H, Hu JJ, Zhang H, Zhou WC. Establishment and characterization of a new human ampullary carcinoma cell line, DPC-X1. World J Gastroenterol 2023; 29(17): 2642-2656
URL https://www.wjgnet.com/1007-9327/full/v29/i17/2642.htm
DOI https://dx.doi.org/10.3748/wjg.v29.i17.2642
Full Article (PDF) WJG-29-2642.pdf
Full Article (Word) WJG-29-2642.docx
The ARRIVE Guidelines 82578-The-ARRIVE-Guidelines-revision.pdf
Manuscript File 82578_Auto_Edited-JLW.docx
Answering Reviewers 82578-Answering reviewers.pdf
Audio Core Tip 82578-Audio core tip.m4a
Biostatistics Review Certificate 82578-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 82578-Conflict-of-interest statement.pdf
Copyright License Agreement 82578-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 82578-Grant application form(s).pdf
Institutional Animal Care and Use Committee Approval Form or Document 82578-Institutional animal care and use committee statement.pdf
Institutional Review Board Approval Form or Document 82578-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 82578-Language certificate.pdf
Video 82578-Video.mp4
Supplementary Material 82578-Supplementary material.pdf
Peer-review Report 82578-Peer-review(s).pdf
Scientific Misconduct Check 82578-Bing-Fan JR-2.png
Scientific Editor Work List 82578-Scientific editor work list.pdf