Publication Name	World Journal of Hepatology
Manuscript ID	84532
Country	United States

Received	2023-03-17 19:01
Peer-Review Started	2023-03-17 19:04
To Make the First Decision
Return for Revision	2023-05-30 19:51
Revised	2023-06-07 02:52
Second Decision	2023-06-13 02:58
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2023-06-13 08:59
Articles in Press	2023-06-13 08:59
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2023-07-04 03:57
Publish the Manuscript Online	2023-07-21 09:10

ISSN	1948-5182 (online)
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Category	Pathology
Manuscript Type	Minireviews
Article Title	Solid-Tubulocystic carcinoma: A new variant of intrahepatic cholangiocarcinoma
Manuscript Source	Invited Manuscript
All Author List	Iván A González, Wenyi Luo and Xuchen Zhang
Funding Agency and Grant Number
Corresponding Author	Xuchen Zhang, MD, PhD, Full Professor, Department of Pathology, Yale University School of Medicine, 300 Cedar Street, New Haven, CT 06511, United States. xuchen.zhang@yale.edu
Key Words	Cholangiocarcinoma; Intrahepatic; Solid-tubulocystic; Cholangioblastic; Inhibin
Core Tip	Solid-tubulocystic variant of intrahepatic cholangiocarcinoma (iCCA) is a recently recognized iCCA variant, which previously was termed as cholangioblastic iCCA. This new variant iCCA predominantly presents in young woman characterized by a heterogenous microscopic appearance with small to medium sized tumor cells with eosinophilic cytoplasm organized in solid, tubular, and cystic growth patterns. One of the defining features is the diffuse expression of inhibin. Recurrent NIPBL::NACC1 gene fusion has been identified in this iCCA variant. Compared to typical iCCAs, patients with this variant iCCA may have a better prognosis with 25% of the cases reported died of disease in 5 years.
Publish Date	2023-07-21 09:10
Citation	González IA, Luo W, Zhang X. Solid-Tubulocystic carcinoma: A new variant of intrahepatic cholangiocarcinoma. World J Hepatol 2023; 15(7): 897-903
URL	https://www.wjgnet.com/1948-5182/full/v15/i7/897.htm
DOI	https://dx.doi.org/10.4254/wjh.v15.i7.897

Full Article (PDF)	WJH-15-897-with-cover.pdf
Full Article (Word)	WJH-15-897.docx
Manuscript File	84532_Auto_Edited-JLW.docx
Answering Reviewers	84532-Answering reviewers.pdf
Audio Core Tip	84532-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	84532-Conflict-of-interest statement.pdf
Copyright License Agreement	84532-Copyright license agreement.pdf
Peer-review Report	84532-Peer-review(s).pdf
Scientific Misconduct Check	84532-Bing-Ma YJ-2.jpg
Scientific Editor Work List	85054-Scientific editor work list.pdf