Publication Name	World Journal of Critical Care Medicine
Manuscript ID	90617
Country	Brazil

Received	2023-12-08 22:06
Peer-Review Started	2023-12-08 22:06
To Make the First Decision
Return for Revision	2023-12-19 01:11
Revised	2023-12-28 04:22
Second Decision	2024-01-22 02:39
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-01-22 05:40
Articles in Press	2024-01-22 05:40
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-02-08 00:35
Publish the Manuscript Online	2024-03-05 06:47

ISSN	2220-3141(online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Critical Care Medicine
Manuscript Type	Retrospective Cohort Study
Article Title	Shock index and its variants as predictors of mortality in severe traumatic brain injury
Manuscript Source	Invited Manuscript
All Author List	Randhall B Carteri, Mateus Padilha, Silvaine Sasso de Quadros, Eder Kroeff Cardoso and Mateus Grellert
Funding Agency and Grant Number
Corresponding Author	Randhall B Carteri, PhD, Postdoc, Professor, Researcher, Department of Nutrition, Centro Universitário CESUCA, Silvério Manoel da Silva, 160-Colinas, Cachoeirinha-RS, Porto Alegre 94935-630, Brazil. rcarteri@outlook.com
Key Words	Head trauma; Critical patient; Neuro-cardio axis; Predictive tool; Clinical practice
Core Tip	Patients who suffer severe head trauma are also affected by altered balance between heart rate and blood pressure which influences oxygen delivery to tissues and the overall cardiac function. Although previous studies indicated that shock index (SI) and its variants could predict the outcomes following traumatic brain injury (TBI) the studies were conducted in patients with different severities of injury. Therefore, when evaluating patients who suffered a severe TBI (sTBI), the SI and its variants are not a viable outcome-predictive tool in sTBI, due to similar responses in both surviving and non-surviving patients. However, the Age multiplied SI was a viable outcome-predictive tool in sTBI, warranting future research in different cohorts.
Publish Date	2024-03-05 06:47
Citation	Carteri RB, Padilha M, de Quadros SS, Cardoso EK, Grellert M. Shock index and its variants as predictors of mortality in severe traumatic brain injury. World J Crit Care Med 2024; 13(1): 90617
URL	https://www.wjgnet.com/2220-3141/full/v13/i1/90746.htm
DOI	10.5492/wjccm.v13.i1.90617

Full Article (PDF)	WJCCM-13-90617-with-cover.pdf
STROBE Statement	90617-STROBE statement.pdf
Manuscript File	90617_Auto_Edited-YJP.docx
Answering Reviewers	90617-Answering reviewers.pdf
Audio Core Tip	90617-Audio core tip.mp3
Biostatistics Review Certificate	90617-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	90617-Conflict-of-interest statement.pdf
Copyright License Agreement	90617-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s)	90617-Informed consent statement.pdf
Institutional Review Board Approval Form or Document	90617-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate	90617-Language certificate.pdf
Peer-review Report	90617-Peer-review(s).pdf
Scientific Misconduct Check	90617-Bing-Fan JR-2.png
Scientific Editor Work List	90617-Scientific editor work list.pdf
CrossCheck Report	90617-CrossCheck report.pdf
CrossCheck Report	90617-CrossCheck.png