Publication Name	World Journal of Ophthalmology
Manuscript ID	9484
Country	Germany

Received	2014-02-13 17:32
Peer-Review Started	2014-02-17 13:59
To Make the First Decision	2014-03-12 16:37
Return for Revision	2014-03-17 16:56
Revised	2014-03-19 15:33
Second Decision	2014-06-11 13:27
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2014-06-11 13:41
Articles in Press	2014-06-11 13:42
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-09-28 17:45
Publish the Manuscript Online	2014-10-20 09:43

ISSN	2218-6239 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Ophthalmology
Manuscript Type	Minireviews
Article Title	Blue light induced retinal oxidative stress: Implications for macular degeneration
Manuscript Source	Invited Manuscript
All Author List	Richard HW Funk, Ulrike Schumann, Katrin Engelmann, Klio A Becker and Cora Roehlecke
Funding Agency and Grant Number
Corresponding Author	Richard HW Funk, Prof. Dr., Institute of Anatomy, TU - Dresden, Fiedlerstrasse 42, Dresden, 01307, Germany richard-funk@tu-dresden.de
Key Words	blue light; oxidative stress; retina; photoreceptor; age related macular degeneration
Core Tip	The mechanisms that can lead to damage and subsequently to degenerative diseases like age related macular degeneration (AMD) remain unclear, especially whether light induced radical stress or damage is a direct interaction of light with photoreceptors or a secondary mechanism. Recently it was shown that after blue light not only the mitochondria in the retinal cells can produce massive amounts of of reactive oxygen species (ROS) but also the outer segments of photoreceptors. Furthermore, there are indications that the outer segments harbour ectopic enzymes of the respiratory chain being an additional source of ROS production. In the light of these novel aspects we have compiled a review revisting the data of oxidative stress in the retina - possibly one cause for development of AMD.
Publish Date	2014-10-20 09:43
Citation	Funk RHW, Schumann U, Engelmann K, Becker KA, Roehlecke C. Blue light induced retinal oxidative stress: Implications for macular degeneration. World J Ophthalmol 2014; 4(3): 29-34
URL	http://www.wjgnet.com/2218-6239/full/v4/i3/29.htm
DOI	http://dx.doi.org/10.5318/wjo.v4.i3.29

Full Article (PDF)	WJO-4-29.pdf
Full Article (Word)	WJO-4-29.doc
Manuscript File	9484-Review.docx
Answering Reviewers	9484-Answering reviewers.pdf
Copyright License Agreement	9484-Copyright assignment.pdf
Peer-review Report	9484-Peer review(s).pdf
Scientific Misconduct Check	9484-CrossCheck.jpg
Scientific Editor Work List	9484-Scientific editor work list.pdf