Publication Name	World Journal of Gastroenterology
Manuscript ID	14443
Country	United States

Received	2014-10-04 14:55
Peer-Review Started	2014-10-04 20:50
To Make the First Decision	2014-10-29 14:54
Return for Revision	2014-11-03 15:00
Revised	2014-11-15 23:33
Second Decision	2015-01-12 13:58
Accepted by Journal Editor-in-Chief	2015-01-14 00:16
Accepted by Executive Editor-in-Chief	2015-01-21 17:15
Articles in Press	2015-01-21 17:32
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-02-11 18:14
Publish the Manuscript Online	2015-03-09 15:58

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Review
Article Title	Hepatosplanchnic circulation in cirrhosis and sepsis
Manuscript Source	Invited Manuscript
All Author List	Meghan Prin, Jan Bakker and Gebhard Wagener
Funding Agency and Grant Number
Corresponding Author	Gebhard Wagener, MD, Associate Professor, Department of Anesthesiology, College of Physicians and Surgeons of Columbia University, P S Box 46 (PH-5), 630 West 168th Street, New York, NY 10032, United States. gw72@columbia.edu
Key Words	Liver cirrhosis; Sepsis; Splanchnic circulation; Hepatic circulation; Hepatic artery buffer response
Core Tip	The prevalence of cirrhosis in critically ill patients is increasing worldwide. Cirrhosis leads to hepatosplanchnic circulatory abnormalities and end-organ damage, which resemble the clinical syndrome of patients with sepsis. The pathophysiology of cirrhosis can both predispose patients to, and exacerbate, sepsis. An understanding of this pathophysiology may assist critical care providers in the development and application of treatment modalities.
Publish Date	2015-03-09 15:58
Citation	Prin M, Bakker J, Wagener G. Hepatosplanchnic circulation in cirrhosis and sepsis. World J Gastroenterol 2015; 21(9): 2582-2592
URL	http://www.wjgnet.com/1007-9327/full/v21/i9/2582.htm
DOI	http://dx.doi.org/10.3748/wjg.v21.i9.2582

Full Article (PDF)	WJG-21-2582.pdf
Full Article (Word)	WJG-21-2582.doc
Manuscript File	14443-Review.docx
Answering Reviewers	14443-Answering reviewers.pdf
Conflict-of-Interest Disclosure Form	14443-Conflict-of-interest statement.pdf
Copyright License Agreement	14443-Copyright assignment.pdf
Peer-review Report	14443-Peer-review(s).pdf
Scientific Misconduct Check	14443-CrossCheck.jpg
Scientific Editor Work List	14443-Scientific editor work list.pdf