Publication Name	World Journal of Biological Chemistry
Manuscript ID	18485
Country	Japan

Received	2015-04-22 09:08
Peer-Review Started	2015-04-22 16:55
To Make the First Decision	2015-05-13 19:29
Return for Revision	2015-05-20 11:22
Revised	2015-05-26 17:38
Second Decision	2015-07-02 09:42
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2015-07-14 10:00
Articles in Press	2015-07-14 10:00
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-08-11 13:28
Publish the Manuscript Online	2015-08-26 11:07

ISSN	1949-8454 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Developmental Biology
Manuscript Type	Review
Article Title	Molecular basis of cleft palates in mice
Manuscript Source	Invited Manuscript
All Author List	Noriko Funato, Masataka Nakamura and Hiromi Yanagisawa
Funding Agency and Grant Number	Funding Agency Grant Number Japan Society for the Promotion of Science 25670774(to Funato N) Japan Society for the Promotion of Science 15K11004(to Funato N)
Corresponding Author	Noriko Funato, DDS, PhD, Research Center for Medical and Dental Sciences, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8510, Japan. noriko-funato@umin.ac.jp
Key Words	Tbx1; Submucosal cleft palate; Incomplete cleft palate; Palatal shelf; Palatogenesis; Knockout mice
Core Tip	Cleft lip and/or palate is one of the most frequent congenital craniofacial anomalies observed. Multifactorial conditions, including genetic and environmental factors, induce the formation of cleft palates. We screened knockout mice with cleft palate phenotypes and observed approximately 180 mice with the anomaly. In order to understand the molecular regulatory mechanisms of palatogenesis and to identify genetic errors that lead to cleft palates, we aimed to review studies performed using knockout mice with cleft palates.
Publish Date	2015-08-26 11:07
Citation	Funato N, Nakamura M, Yanagisawa H. Molecular basis of cleft palates in mice. World J Biol Chem 2015; 6(3): 121-138
URL	http://www.wjgnet.com/1949-8454/full/v6/i3/121.htm
DOI	http://dx.doi.org/10.4331/wjbc.v6.i3.121

Full Article (PDF)	WJBC-6-121.pdf
Full Article (Word)	WJBC-6-121.doc
Manuscript File	18485-Review.docx
Answering Reviewers	18485-Answering reviewers.pdf
Audio Core Tip	18485-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	18485-Conflict-of-interest statement.pdf
Copyright License Agreement	18485-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	18485-Language certificate.pdf
Peer-review Report	18485-Peer-review(s) .pdf
Scientific Misconduct Check	18485-Scientific misconduct check.pdf
Scientific Editor Work List	18485-Scientific editor work list.pdf